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 and since it is well known that the disease is hereditary, and develops in successive generations, the fact that such marriages are sanctioned is scandalous and infamous. The supply, therefore, is kept up from two sources. The first contingent is derived from apparently healthy parents; the second, by inheritance from diseased persons. The origin of the first is obscure; and before its quota can be cut off, or even diminished, the mystery which envelopes it must be dissipated. The remedy for the second is obvious, and is in the hands of the authorities—particularly in those of the clergy. Marriage must be prohibited to all who are affected; the most extreme cases must be placed under restraint; and crétins whose origin is illegitimate must be subject to disabilities. Nothing short of the adoption of these measures will meet the case. Useless it will be, so long as the primary sources of the disease are untouched, to build hospitals, to cleanse dwellings, to widen streets, or to attempt small ameliorations of the social circumstances of the natives. All of these things are good enough in themselves, but they are wholly impotent to effect a radical change.

No satisfactory conclusion will be arrived at regarding the origin of crétinism until the pedigrees of a large number of examples have been traced. The numerical test is the only one which is likely to discover the reality. The necessary inquiries are beyond the powers of private persons, and their pursuit will be found