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XLI] In tracing the bowel upwards the thickening became less marked and more patchy. The liver and bowel cut gritty on section. The bladder was thickened where adhesions had formed with the rectum, but elsewhere it was healthy, and nowhere was the vesical mucosa diseased. Sections of the liver, mesenteric glands, and bowel were found to contain the ova of S. japonicum.

In a case from Katayama, described by Tsunoda and Shimamura, the necropsy revealed, besides the ordinary lesions in the liver, intestine, and pancreas, thickening with hæmorrhagic infiltration of both the dura and pia mater. In the brain itself a number of wedge-shaped sclerosed areas of greyish colour, and surrounded by some ecchymosis, were found. In the lenticular nucleus, optic thalamus, and internal capsule of the left side there was an area of softening the size of a walnut. On histological examination these areas were found to contain ova embedded in neuroglia and surrounded by softened and degenerated brain tissue. Similar ova were found in the membranes, and a few in the right hemisphere and in the choroid plexuses of the lateral ventricles. In connection with these lesions the