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v] readily set up by chill and prone to terminate in abscess of the lung or to become associated with empyema, extensive sloughing phagedæna, and other forms of gangrene such as noma; or pernicious fever may supervene at any time and rapidly carry off the subject of advanced malarial cachexia.

Tubercular and syphilitic disease not infrequently concur with malaria; in fact, the latter may powerfully predispose to local manifestations of either of the two former, and vice versa—— a complication as to which the practitioner should always be on his guard.