Page:Treatise on poisons in relation to medical jurisprudence, physiology, and the practice of physic (IA treatiseonpoison00chriuoft).pdf/459

 There is no doubt, however, but many plants of the present order, as well as their active principles, have a totally different and very peculiar action. They produce violent spreading inflammation of the subcutaneous cellular tissue, and acute inflammation of the stomach and intestines, without entering the blood; and death is the consequence of a sympathy of remote organs with the parts directly injured.

As to their forming a natural order of poisons, it is evident, that if a general view be taken of their properties, they are distinguished by obvious phenomena from the three orders hitherto noticed. But if their effects on man be alone taken into account, when of course their influence on the external surface of the body must be left out of view, nothing will be discovered to distinguish them from several of the metallic irritants.

The symptoms occasioned in man by the irritant poisons of the vegetable kingdom, are chiefly those indicating inflammation of the villous coat of the stomach and intestines. When taken in large doses, they excite vomiting soon after they are swallowed; by which means the patient's life is often saved. But sometimes, like the mineral poisons that possess emetic properties, the vegetable acrids present a singular uncertainty in this respect: they may be retained without much inconvenience for some length of time. If this should happen, or if the dose be less, in which case vomiting may not be produced at all, or if only part of a large dose be discharged at an early period by vomiting,—the other phenomena they give rise to are sometimes fully developed. The most conspicuous symptom then is diarrhœa, more or less profuse. The diarrhœa and vomiting are commonly attended by twisting pain of the belly, at first remittent, but gradually more constant, as the inflammation becomes more and more strongly marked. Tension, fulness and tenderness of the belly, are then not unfrequent. The stools may assume all the characters of the discharges in natural inflammation of the intestinal mucous membrane, but an additional character worthy of notice is the appearance of fragments of leaves or flowers belonging to the plant which has been swallowed. At the same time there is generally excessive weakness. Sometimes, too, giddiness and a tendency to delirium have been observed. But the latter symptoms are rare: if they occurred frequently, it would be necessary to transfer any poison which produced them to the class of narcotico-acrids.

The properties now mentioned have long ago attracted the attention of physicians, and led them to introduce many vegetable irritants into the materia medica. In fact they comprehended a great number of the most active, or, as they are technically called, drastic purgatives. Among others, elaterium, euphorbium, gamboge, colocynth, scammony, croton, jalap, savin, stavesacre, are of this description. The effect of most of them, however, is so violent and uncertain, that few are now much used except when combined with other milder laxatives.

The morbid appearances they leave in the dead body are the same