Page:Treatise on poisons in relation to medical jurisprudence, physiology, and the practice of physic (IA treatiseonpoison00chriuoft).pdf/397

 other hand, Dr. Nasse of Berlin says a patient of his, who had taken twenty grains of oxide of zinc daily till 3247 grains were swallowed, was attacked with paleness, emaciation, weakness of intellect, obstinate constipation, coldness and œdema of the limbs, extreme dryness of the skin, and a thready scarcely perceptible pulse. But he quickly recovered under the use of laxatives and tonics.

Sulphate of zinc is said to have proved fatal when applied externally. In Pyl's memoirs there is a case of this nature, which was attributed to sulphate of zinc having been used as a lotion for a scabby eruption on the head. The subject was a child, six years old, and otherwise healthy. The wash, which was a vinous solution, had not been long applied before the child complained of acute burning pain of the head, which was followed by vomiting, purging, convulsions, and death in five hours. The cause of these symptoms, though the particulars of the case were ascertained judicially by an able medical jurist, Dr. Opitz of Minden, is nevertheless very doubtful, as daily use is made of the salt for similar purposes without any such effect. Appearances of congestive apoplexy were found within the skull; and the reporter ascribes death to the wash having produced repulsion of the cutaneous disease, and determination of blood to the head.

The only opportunities which have occurred of observing the morbid appearances after poisoning with sulphate of zinc taken internally, are the cases by Metzger, Mertzdorff, and Werres.

In the first, which was a mixed case, the only appearances of note were slight inflammation in the stomach, and excessive gorging of the lungs with fluid blood; from which Metzger oddly enough concludes that the child was suffocated by the vomiting. In the second case, Mertzdorff found the stomach and intestines, but particularly the latter, contracted,—their outer surface healthy—the inner membrane of the stomach grayish-green, with several spots of effused blood, and greenish, fluid contents,—the inner membrane of the small intestines similarly spotted,—the rest of the body quite natural. It has been already mentioned that Mertzdorff detected the poison in the body. He found it not only in the contents, but likewise in the coats of the stomach and intestines. In the third, Werres found a reddish-brown patch and some vascularity in the stomach.

Of Poisoning with Iron.

In previous editions of this work the preparations of iron were arranged among those substances which are not usually considered poisonous, but which may nevertheless prove injurious when taken in large quantity. But the soluble salts of iron, although not very active, seem sufficiently so to entitle them to a regular place among poisons; and one of them, the sulphate, has actually been used, as will presently appear, for the purpose of committing murder.