Page:Treatise on poisons in relation to medical jurisprudence, physiology, and the practice of physic (IA treatiseonpoison00chriuoft).pdf/345

 The corrosion caused by mercury, if examined before the slough is thrown off, will be found to possess an important peculiarity: the disorganized tissue yields mercury by chemical analysis. Professor Taddei repeatedly obtained the metal from the membranes of animals which he had poisoned with corrosive sublimate. It is probable that mercury may be thus detected although death may not have taken place for some time after the poison was swallowed. For the slough was found adhering in one of Mr. Valentine's cases, where life was prolonged for seventy hours; and it was not entirely removed even in eight days in one of the cases described by Dr. Venables.

Although, however, it is sometimes possible to find the poison in the stomach, the medical jurist must not perhaps expect to find it so often in the present instance as in that of poisoning with arsenic. For on account of its greater solubility corrosive sublimate cannot adhere with such obstinacy to the villous coat, and is therefore more subject to be discharged by vomiting. Nevertheless, the insoluble compound formed by antidotes may adhere to the coats like arsenic, and so resist the tendency of vomiting to displace them. In Devergie's case, notwithstanding twenty-three hours of incessant vomiting, although no poison could be detected in the fluid contents of the stomach, it was distinctly found in small whitish masses that lay between the folds of the rugæ.

It may be here farther observed that corrosive sublimate, as well as other salts of mercury, may undergo in the alimentary canal after death the same change which is produced in arsenic from the gradual action of hydrosulphuric acid gas. It may be converted into the sulphuret. I am not acquainted indeed with any actual instance of such conversion; but that it may occur we can scarcely doubt, not merely from theoretical considerations, but likewise because Orfila met with an instance where calomel taken daily in a case of gastro-cephalitis was discharged by stool in the form of a black sulphuret.

Another important consideration is, that corrosive sublimate may be decomposed and reduced to the metallic state by the admixture of various substances either given at the same time or subsequently, and the longer the inspection is delayed, the more complete will be the decomposition which is accomplished. Iron, zinc, and other metals are the most active of these substances.

The other forms of destruction of the coats of the alimentary canal is common ulceration, either such from the beginning, or what was originally corrosion converted into an ulcer in consequence of the disorganized spot being thrown off by sloughing.

I have seen this appearance to an enormous extent in the great intestines of a man who survived nine days. Numerous large, black, gangrenous ulcers, just like those observed in bad cases of dysentery,