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 hood, and did incredible damage until itself extinguished about 1822.

Thus lay the “old chapel,” desecrated and forsaken, until that year of 1783, memorable in Harvard annals as the time when the College burgeoned into a true university by opening the first of its professional schools. The Medical School, the earliest in New England, resulted from the unwearied efforts of Dr. John Warren of the class of 1771. To his eagle eye the rising tiers of seats in Holden offered the nearest approach to an operating amphitheatre obtainable in those days, when lecture-rooms were small and scarce—obtainable, too, at little expense save some rough repairs and the construction of a tiny chimney to permit the introduction of a stove.

In consequence, having served the purposes of church, state, and army, Madam Holden’s gift next came under the domain of medicine. Among all its transformations, this phase was not only the most memorable, as the