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were constantly called upon to throw light upon unusual phenomena. His idea that responsibility is essential for serious study and for real development has borne fruit in the students upon whom it has been his custom to place as much as could safely be carried. More widespread in its influence than his personal teaching has been that of the many editions of his text-book. No volume on internal medicine has ever had a larger sale or met with more universal commendation than Osier's 'Principles and Practise.' It is a model, at the same time, of brevity and comprehensiveness. Clear and practical, it reveals an unusual power to sift out non-essentials. It is rich in records of personal experience but it embodies also the pith of the wisdom of medical minds of all times and of all countries. Through marvelous industry and constant contact with young men in the various