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Rh the beginning of a successful professional career. Another son, Dr., the subject of this sketch, was born in Philadelphia, August 21, 1843.

Dr. Pepper received his educational training solely in the city of his birth, having graduated from the college department of the University of Pennsylvania in 1862, in the same class with Provost Charles C. Harrison, Thomas McKean, Dr. Persifor Fraser, and many other men prominent in university circles. He graduated from the Medical School in 1864, and at once began the practice of medicine. His connection with the University of Pennsylvania began in 1868, when he was appointed lecturer on morbid anatomy. From 1870 to 1876 he was lecturer on clinical medicine. In 1876 Dr. Pepper was given a full professorship of clinical medicine, in which he continued until 1887, when he succeeded Dr. Alfred Stillé in the chair of the Theory and Practice of Medicine.

During this early period of his career Dr. Pepper labored with untiring zeal in the practice of his profession, and he also became eminently successful as a teacher. In 1877 he set forth his views on higher medical education in an address at the opening of the one hundred and twelfth course of lectures in the University Medical School. At that time a very low standard existed in the medical schools of our country, and Dr. Pepper, in his address, urged the following reforms:

 1. The establishment of a preparatory examination. 2. The lengthening of the course to at least three full years. 3. The careful grading of the course. 4. The introduction of ample practical instruction of each student both at the bedside and in laboratories. 5. The establishment of fixed salaries for the professors, so that they may no longer have any pecuniary interest in the size of their classes.

It was a source of gratification to Dr. Pepper that he lived to see all these reforms in medical education adopted. On the extension of the medical course to four years he subscribed $50,000 toward a permanent endowment of $250,000. As early as 1871 he began to urge the establishment of a university hospital, the subject being first discussed in a conversation with Dr. H. C. Wood and Dr. William F. Norris. An appeal was made to the public, and Dr. Pepper was made chairman of a finance committee. By May, 1872, a splendid site and $350,000 for building and endowment had been secured. Dr. Pepper was selected as chairman of