Page:Popular Science Monthly Volume 50.djvu/820

 798 The administration of alcohol was begun May 12th, six cubic centimetres of chemically pure alcohol, diluted to forty per cent with water and mixed with their breakfast, being given to Tipsy and Bum. No appreciable effect was produced. Accordingly, the



dose was increased daily until May 24th, when they received twenty-five cubic centimetres apiece. This caused rather pronounced intoxication, but nothing approaching stupor. Both dogs appeared next morning as bright and playful as ever.

My intention at this time was to run the experiment along the line of light daily intoxication, but, with Dr. Billings's concurrence, what seemed to be a better physiological limit was adopted. It was decided to give as large doses as possible, short of producing noticeable symptoms of intoxication. Accordingly, the amount was reduced to fifteen cubic centimetres, which was increased to twenty cubic centimetres by June 10th, and thereafter, as the dogs grew, up to thirty-five cubic centimetres apiece by the