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human calculation as to the expediency of certain plans of operation which have suggested themselves to me in the course of my movements about this great city, or when I am reflecting upon the condition of humanity at large. Now, I frankly confess that it is in such a balance that I have from time to time weighed thy interesting concern. I have personally appealed to some of the most intelligent and liberal-minded ladies of my acquaintance how far the services of a well-educated female physician would be appreciated by them. The response uniformly is, "Mrs. Gove and Mrs. Wright were unfit to teach, nor could any female become acceptable to us, either as a teacher or practitioner of medicine." This language is stronger than I should be willing to use myself. It is an interesting matter of history, and one which may afford some encouragement to reformers to persevere, when they are assured that their cause has its foundation in truth, justice, and mercy; that Saul, who had been most bitter in his persecution of Christians, joining in the popular outcry against the great Innovator, not only himself became a convert to the new faith, but under the name of Paul, for the balance of his active life, employed his powerful talents in the extension of the very doctrines which in his misguided zeal he had laboured to subvert. I confess, my dear lady, that I with thee see many difficulties in the way to the attainment—firstly, to the acquisition of the kind and amount of education thou art aware is necessary as a capital stock with which to begin the enterprise which has been opened to thy mind; secondly, that after years spent in the attempt the popular mind will be found barred against thy mission of love and humanity; but I beg thee to believe with me that if the project be of divine origin and appointment it will sooner or later surely be accomplished. Thus, in the language of Gamaliel on another