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30  should have followed on such an attack. About a fortnight later she had a fresh seizure, of a very similar kind. This time, however, the symptoms were aggravated, and accompanied by others of a more alarming character. Of these the most conspicuous were nausea, vomiting, violent perspiration, and increasing tendency to diarrhœa. The patient also complained of great sinking of the heart, and of a terrible lowness of spirits, almost amounting to a conviction that death was at hand. In the course of another fortnight or three weeks there was a fresh recurrence of the symptoms. The tongue, which in the former attacks had been clammy and dry, was now covered thickly with dirty mucus, and there was a greatly increased flow of saliva. The condition of the tongue became greatly aggravated as the disease progressed, the mouth and throat becoming ultimately very sore, with great constriction of the latter. The abdomen was distended, and very tender to the touch, the liver also being very full and tender. Pulse low and rapid, decreasing in fulness as the disease progressed, and reaching finally to 130 or 140; and the depression of spirits and sinking at the heart considerably increased. The patient appeared to be daily losing strength, and at each attack, which seemed to return periodically at intervals of about a fortnight, the same symptoms appeared more severely than before. Mr. Anderton seemed to be in the deepest distress. From the time when the symptoms first became serious, he hardly ever left her side, administering both food and medicine with his own hand. So far as I am aware, Mrs. Anderton took nothing of any kind from any other person throughout the greater portion of her illness. I have heard her say this herself, in his presence, shortly before her death. For the last few weeks she took scarcely any nourishment, and could with difficulty swallow her medicine. The principal cause of this difficulty lay in the extreme nausea which followed any attempt to swallow, but it was greatly increased by the painful and constricted state of the throat, which was extremely rough and raw, and rendered swallowing very painful. As the disease progressed the vomited matter became strongly coloured with bile, and was of a strong yellow colour. The opressionoppression [sic] on the heart also increased, until at length respiration was almost impeded. The heart and pulses also gradually lost power, and latterly the lower portion of the body was almost paralysed, the limbs being stiff, and the whole frame, from the waist downward, very heavy and cold. The patient also suffered from severe cold perspirations, as well as from heat and irritation of the upper portion of the body, and from entire inability to sleep. A very remarkable feature in the case was, that notwithstanding this general sleeplessness, each fresh attack of the malady was preceded by a sound slumber of some hours duration, from which she appeared to be aroused by the return of the more active symptoms of the disorder. I tried all the usual remedies indicated by such symptoms, but without any permanent effect, and I was a good deal perplexed by the anomalous appearance of the case, and especially by its intermittent character, the symptoms recurring, as I have said, with increased severity, at regular intervals of about a fortnight. I mentioned my difficulty to Mr. Anderton, and asked if he would wish further advice. At his urgent request I consented, though with some hesitation, to meet Baron R**, who holds, as I was given to understand, a regular diploma from several of the foreign Universities, but whose practice has been of a somewhat irregular character. I first consulted with him on the 12th July.

[Dr. Dodsworth here details at some length how he became convinced of the Baron’s great skill and knowledge of chemistry, and was finally persuaded to meet him in consultation.]

After examination of the patient, however, and some conversation as to the nature of the symptoms and of the remedies employed, I had some difficulty in drawing from him (the Baron) any expression of opinion. He appeared, however, to agree entirely in the course hitherto pursued, and after some further conversation we separated. The consultation took place in Mrs. Anderton’s dressing-room, and in passing by the wash-hand stand on his way out, the Baron suddenly took up a small bottle which was standing there, and turning sharply upon me, asked “if I had tried that?” On taking it from his hand, I found that it contained tincture of tannin, a preparation much used for the teeth. I was somewhat startled by the suddenness of the question, and replied in the negative, on which the subject dropped. On my way home, however, I was again struck by the peculiarity of the Baron’s manner in putting the question; and on thinking the matter over, the idea suddenly flashed across me that tannic acid was the antidote to antimony, and that the symptoms of poisoning by tartarised antimony, to which attention had just been drawn by Professor Taylor, in the case of the Rugely murder, closely resembled in many respects those under which Mrs. Anderton was then suffering. At the first moment this supposition seemed to account for all the mysterious part of the case; but on reflection the difficulty returned, for it seemed impossible that the poison could have been administered by any one but Mr. Anderton himself, and I felt it still more impossible to suspect him of such an act, in face of the evident and extreme affection existing between them. On mature reflection, however, I determined on trying, at all events for a time, the course suggested by the Baron, and accordingly exhibited large doses of Peruvian bark, together with other medicines of the same kind. My suspicions were at first increased by the improvement apparently effected by these remedies, and I took occasion to ask Mr. Anderton, in a casual way, in presence of the nurse and one of the servants, whether he had any emetic tartar or antimonial wine in the house. The manner of his reply entirely removed from my mind any idea that either of those present at least had any knowledge of such an attempt as seemed implied by the Baron, and on seeing that gentleman a day or two after, I questioned him as to the true bearing of his suggestion. He disclaimed, however, any such meaning as I had been