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. 18, 1862.]

Fred Holdsworth located in one of the many streets leading from the Strand towards the river. He had secured rooms for me in the same house; and although I did not like the place (it was noisy all day in front with heavy carts; and noisy all night behind with cats), still, as he approved of it, and as I wanted company, I stayed, and was soon reconciled. I rapidly became immersed in my studies, and Holdsworth seemed also immersed in pleasure and all the jollities of medical student life. We were very unlike in disposition, and probably for that very reason were the better friends. We never had the semblance of a quarrel, and consequently lived on very comfortably. He could not comprehend my wish to study chemistry only for the love of science. When in his sensible moments, however, I could see that he was very fond of his profession, and he was continually advising me to enter myself as a student of medicine and surgery. But I had no taste for therapeutics.

Many of his studies, however, led him in the same direction as myself, and at last he had to undergo the ordeal of some examination which he was desirous of passing creditably; and to do him justice, he worked very hard. He used to sit in the house at night (a very unusual thing for him), and pore over his books, while I, on the other side of the table, was arranging my notes, or jotting down memoranda of the experiments which I had completed during the day. He found me of some assistance to him in his chemical studies, and was in the habit of consulting me at times. I remember a conversation that we had one evening which led in the end to very strange and awful results, brought me misery and pain, and led me close to the gate of death.

We had been conversing on that mysterious and fascinating portion of chemistry which relates to attraction and repulsion, chemical combinations and decompositions and elective affinity. I recollect now that I startled myself by some of the strange fancies which I indulged in.

Holdsworth had confessed that he had been perplexed in trying to class together several substances which had been placed before him in a mixed solution. He could not arrange the acids and bases to his satisfaction, and complained bitterly that he believed it was all empiricism to say that one could tell accurately which substances were in conjunction. After trying to explain the subject to him, I remember saying that if he would listen to me for a short time, he might be able to gain some hints which might be useful to him.

“You must have observed,” I said, “that some chemical substances are of such a nature that