Page:NIOSH Manual of Analytical Methods - 9106.pdf/20

 METHAMPHETAMINE. . .on Wipes by Liquid-Liquid Extraction: METHOD 9106, Issue 1, dated 17 October 2011 - Page 20 of 31

Table 10. Gas chromatographic retention times for chlorodifluoroacetyl derivatives of amphetamines, precursors, adulterants, and miscellaneous drugs of abuse.(1) GC Peak No.(2) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41

Compound Nicotine (DL)-Amphetamine-D11(I$)(7) (DL)-Amphetamine Phenethylamine(8) Phentermine(8) N-Methyl pseudoephedrine(9) N-Methyl pseudoephedrine(9) N-Methyl phenethylamine (I$)(7) (DL)-Methamphetamine-D14 (I$)(7) (DL)-Methamphetamine Fenfluramine(8) S-(-)-Cathinone (from Khat plant) Bupropion (Wellbutrin®, Zyban®) N-Ethyl amphetamine Ecgonine, methyl ester S-(-)-Methcathinone (“Cat”) Norpseudoephedrine (Cathine) (±)-Norephedrine Aminorex Dibromooctafluorobiphenyl (I$)(7) N-Propyl amphetamine (I$)(7) 4-Methoxyamphetamine 4-Phenyl-1-butylamine (I$)(7) 1S,2R(+)-Ephedrine-D3 (I$)(7) (DL)-Ephedrine Acetaminophen(8) Methyl phenidate (Ritalin®) Pseudoephedrine Meperidine (Demerol® etc.) Atropine (±)-MDA Caffeine(8) N,N-Dimethyltryptamine (DMT) (±)-BDB Ketamine (“special K”)(8,11) Lidocaine(8) Trifluoromethylphenyl piperazine(11) Benzyl piperazine(11) (“Legal XTC”) Phencyclidine-D5 (I$)(7) Phencyclidine (PCP) MDMA(11)

Recommended Quantification (1’) and Confirmation(2’, 3’) Ions (m/z)(3) 1’ 2’ 3’ 84 133 162 160 128 162 156 118 158 104 91 170 172 132 134 162 75 72 156 104 158 177 98 179 170 172 118 184 186 159 105 77 132 44 100 111 184 186 118 182 82 311 170 105 172 156 158 246 156 158 246 107 79 232 296 456 454 198 156 200 121 148 78 176 104 173 175 85 170 172 260 108 221 263 84 56 91 170 172 260 71 247 172 124 94 103 135 162 291 194 109 67 58 129 102 135 176 170 180 182 209 86 58 120 200 145 172 91 197 175 205 96 246 200 242 243 170 162 135

Retention Relative Time in Retention Form(4) Minutes Time(5) parent 8.92 0.396 derivative 10.26 0.800 derivative 10.34 0.807 derivative 10.38 0.810 derivative 10.52 0.821 derivative 10.54 0.822 parent abt 11 0.86 derivative 11.37 0.887 derivative 11.70 0.913 derivative 11.79 0.920 derivative 11.83 0.923 derivative 11.99 0.935 parent 12.14 0.947 derivative 12.22 0.953 derivative 12.36 0.964 derivative 12.38 0.966 bis-derivative 12.46 0.972 bis-derivative 12.49 0.974 derivative (-CN) 12.70 0.991 parent 12.82 1.000 derivative 12.97 1.012 derivative 13.22 1.031 derivative 13.27 1.035 derivative 13.44 1.048 bis-derivative 13.48 1.052 derivative 13.67 1.066 parent 13.81 1.077 bis-derivative 13.93 1.087 parent 13.99 1.091 parent (-H2O) 14.25 1.112 derivative 14.36 1.120 parent 14.84 1.158 derivative 14.97 1.168 derivative 15.11 1.179 parent 15.20 1.186 parent 15.28 1.192 derivative 15.46 1.206 derivative 15.54 1.202 parent 15.59 1.216 parent 15.62 1.218 derivative 15.66 1.221

Relative Retention Time(6) 0.757 0.870 0.877 0.880 0.892 0.894 0.93 0.964 0.992 1.000 1.003 1.017 1.030 1.036 1.048 1.050 1.057 1.059 1.077 1.087 1.100 1.121 1.126 1.140 1.143 1.159 1.171 1.182 1.187 1.209 1.218 1.259 1.270 1.282 1.289 1.296 1.318 1.318 1.322 1.325 1.328

Table 10 continued,

Method rev. 1.1.1

NIOSH Manual of Analytical Methods (NMAM), Fifth Edition