Page:NIOSH Manual of Analytical Methods - 5523.pdf/1

 GLYCOLS

FORMULA: Table 1

5523

MW: Table 1

METHOD: 5523, Issue 1

CAS: Table 1

EVALUATION: PARTIAL

OSHA : No PEL NIOSH: No REL ACGIH: C 50 ppm (ethylene glycol) (1 ppm = 2.54 mg/m3 @ NTP)

NAMES & SYNONYMS:

PROPERTIES:

(1) ethylene glycol: 1,2-ethanediol; (3) 1,3-butylene glycol: 1,3-butanediol

XAD-7 OVS tube (glass fiber filter, 13-mm; XAD-7, 200mg/100mg)

Issue 1: 15 May 1996

See Table 1

(2) propylene glycol: 1,2-propanediol (4) diethylene glycol: 2-hydroxyethyl ether, 2,2'oxydiethanol

SAMPLING SAMPLER:

RTECS: Table 1

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTES:

compounds above

DESORPTION:

2 mL methanol; ultrasonicate 30 min

INJECTION VOLUME:

1 µL

FLOW RATE: 0.5 to 2 L/min VOL-MIN: 5L -MAX: 60 L SHIPMENT: SAMPLE STABILITY:

pack cold for shipment

28 days @ 5 C [1] ethylene glycol 14 days @ 5 C [1]

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

250 C 300 C 40 C, 8 C/min to 230 C

CARRIER GAS:

He2 @ 2.4 to 2.6 mL/min

COLUMN:

Rtx-35 fused silica capillary, 30 m, 0.53-mm ID, 3-µm film

CALIBRATION:

solutions of glycols in methanol

RANGE STUDIED: see EVALUATION OF METHOD

RANGE:

15 to 800 µg/sample

BIAS:

ESTIMATED LOD: see Table 2

BLANKS:

2 to 10 field blanks per set ACCURACY

see EVALUATION OF METHOD

OVERALL PRECISION ( ACCURACY:

rT

): not determined

PRECISION ( r):

0.04 to 0.09 [1]

not determined

APPLICABILITY: Under the GC parameters given in the method, the glycols listed above are baseline separated and can be identified based on retention time and quantified. Hexylene glycol can be determined by this method; however, no sampling or analytical evaluation has been conducted. INTERFERENCES:No specific interferences were identified. The method yields baseline separation for all analytes. OTHER METHODS: This method replaces NMAM 5500 [2], which was found deficient in the collection of ethylene glycol in aerosol form. Also ethylene glycol was not separated from propylene glycol by the chromatography.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition