Page:NIOSH Manual of Analytical Methods - 5510.pdf/1

 CHLORDANE

C10 H6Cl8

MW: 409.80

METHOD: 5510, Issue 2

5510

CAS: 57-74-9

RTECS: PB9800000

EVALUATION: FULL

OSHA : 0.5 mg/m 3 (skin) NIOSH: 0.5 mg/m 3 (skin); carcinogen; Group I Pesticide ACGIH: 0.5 mg/m 3 (skin), suspect human carcinogen

Issue 1: 15 May 1989 Issue 2: 15 August 1994

PROPERTIES:

liquid; d 1.59 to 1.63 g/mL @ 25 °C; BP 175 °C; VP 0.0013 Pa (1.0 x 10 -5 mm Hg) @ 20 °C

SYNONYMS: 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane and isomers; Toxichlor; Octachlor

SAMPLING SAMPLER:

MEASUREMENT

FILTER AND SOLID SORBENT TUBE (0.8-µm cellulose ester membrane; Chromosorb 102, 100/50 mg)

FLOW RATE:

0.5 to 1 L/min

VOL-MIN: -MAX:

10 L @ 0.5 mg/m 3 200 L

SHIPMENT:

routine

SAMPLE STABILITY:

> 1 week @ 25 °C [1]

FIELD BLANKS:

2 to 10 field blanks per set

MEDIA BLANKS:

2 per set

BULK SAMPLE:

required

TECHNIQUE:

GAS CHROMOTOGRAPHY, ELECTRON CAPTURE DETECTOR (GC/ECD)

ANALYTE:

Chlordane

EXTRACTION:

10 mL toluene, stand 30 min

INJECTION VOLUME: 2 µL TEMPERATURE-INJECTION: -DETECTOR: -COLUMN: CARRIER GASES: mL/min COLUMN:

RANGE: 3

RANGE STUDIED:

0.16 to 1.17 mg/m [1,2] (120-L samples)

BIAS:

3.0%

ˆ rT): OVERALL PRECISION (S

0.070 [1,2]

ACCURACY:

± 15.3%

95% argon/5% methane @ 75

2 m x 4-mm ID glass packed with 1.5%, SP2250/1.95% SP2401 on 100/120 mesh

CALIBRATION:

ACCURACY

250 °C 300 °C 205 °C

solution of analyte in toluene or hexane with internal standard 5 to 150 µg per sample [2]

ESTIMATED LOD: 0.1 µg per sample [3] PRECISION (Sr):

0.02 @ 6 to 120 µg per sample [2]

APPLICABILITY: The working range is 0.04 to 1.2 mg/m 3 for a 120-L sample. Chlordane, accompanied by a mixture of penta-, hexa-, hepta-, and nonachlorinated compounds, is defined by a group of five chromatographic peaks. It is necessary to de termine the percentage of Chlordane and its isomers in the standards used.

INTERFERENCES: None identified; an alternate column is 2 m x 2-mm ID glass packed with 3% QF-1 on 100/120 mesh Chrom Q.

OTHER METHODS: This is NIOSH method S278 in a revised format. [2]

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94