Page:NIOSH Manual of Analytical Methods - 5012.pdf/1

 EPN

C14 H14 NO4PS

W: 323.31

METHOD: 5012, Issue 2

5012

CAS: 2104-64-5

RTECS: TB1925000

EVALUATION: FULL

OSHA : 0.5 mg/m 3 (skin) NIOSH: 0.5 mg/m 3 (skin); Group I Pesticide ACGIH: 0.5 mg/m 3 (skin)

PROPERTIES:

Issue 1: 15 May 1989 Issue 2: 15 August 1994

solid; MP 36 °C; d 1.268 g/mL @ 25 °C VP 0.04 Pa (0.0003 mm Hg, 5 mg/m 3) @ 100 °C

SYNONYMS: phenylphosphonothioic acid O-ethyl-O,p-nitrophenyl ester

SAMPLING

MEASUREMENT

SAMPLER:

FILTER (glass fiber)

TECHNIQUE:

GAS CHROMATOGRAPHY, FLAME PHOTOMETRIC

FLOW RATE:

1 to 2 L/min

ANALYTE:

EPN

VOL-MIN: -MAX:

15 L @ 0.5 mg/m 3 700 L

DESORPTION:

15 mL isooctane

INJECTION VOLUME:

5 µL

FIELD TREATMENT:

transfer filters within 1 h of sampling to vial

SHIPMENT: SAMPLE STABILITY:

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

215 °C 215 °C 205 °C

in vials

at least 7 days @ 25 °C

CARRIER GAS:

N 2 or He, 60 mL/min

COLUMN:

2 m x 6-mm glass, packed with 3% OV-1 on 100/120 mesh Gas Chrom Q

CALIBRATION:

solutions of the EPN in isooctane

RANGE:

6 to 170 µg per sample

ACCURACY RANGE STUDIED:

0.3 to 1.2 mg/m 3 [1] (120-L samples)

BIAS:

0%

ˆ ): 0.06 [1,2] OVERALL PRECISION (S rT ACCURACY:

ESTIMATED LOD: 2 ng per sample [1] PRECISION (Sr):

0.04 [1]

± 11.4%

APPLICABILITY: The working range is 0.05 to 1.5 mg/m 3 EPN for 120-L air samples. Malathion and Parathion have also been determined by this procedure.

INTERFERENCES: None known.

OTHER METHODS: This method replaces Method S285 [2]. The method of Hill and Arnold [3] has also been used for analysis of pesticides. Method 5600 is an alternative method for organophosphorus pesticides.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94