Page:NIOSH Manual of Analytical Methods - 5009.pdf/1

 BENZOYL PEROXIDE

(C6H5CO)2O2

MW: 242.22

METHOD: 5009, Issue 2

CAS: 94-36-0

5009

RTECS: DM8575000

EVALUATION: FULL

OSHA : 5 mg/m 3 NIOSH: 5 mg/m 3 ACGIH: 5 mg/m 3

PROPERTIES:

Issue 1: 15 February 1984 Issue 2: 15 August 1994

solid; MP 103 °C; d 1.334 g/mL @ 25 °C VP not significant; autoignition temperature 80 °C

SYNONYMS: dibenzoyl peroxide, benzoyl superoxide

SAMPLING

MEASUREMENT

SAMPLER:

FILTER (0.8-µm cellulose ester membrane)

TECHNIQUE:

HPLC, UV DETECTION

FLOW RATE:

1 to 3 L/min

ANALYTE:

benzoyl peroxide

VOL-MIN: -MAX:

40 L @ 5 mg/m 3 400 L

EXTRACTION:

ethyl ether, 10 mL

INJECTION VOLUME: 20 µL

SHIPMENT:

refrigerated

PRESSURE-COLUMN: 9000 kPa (1300 psi)

SAMPLE STABILITY:

9% loss from filter after 1 week @ 25 °C

MOBILE PHASE:

70/30 methanol/water; 1.6 mL/min

DETECTOR:

UV photometer @ 254 nm

BLANKS:

2 to 10 field blanks per set COLUMN:

250 mm x 3 mm-ID stainless steel; Spherisorb ODS (spherical silica particles with 5% bonded coating of octadecyl groups) or equivalent

CALIBRATION:

benzoyl peroxide in ethyl ether

ACCURACY RANGE STUDIED:

3 to 19 mg/m 3 [1] (90-L samples)

BIAS:

- 0.52%

ˆ ): OVERALL PRECISION (S rT

RANGE:

0.2 to 1.7 mg per sample [1]

ESTIMATED LOD:

0.01 mg per sample [2]

PRECISION (Sr):

0.024 [1]

0.060 [1]

ACCURACY:

± 11.82%

APPLICABILITY: The working range is 2 to 19 mg/m 3 for a 90-L air sample.

INTERFERENCES: None identified.

OTHER METHODS: This is Method S253 [3] in a revised format. A non-specific gravimetric method and a non-specific colorimetric method appear in the criteria document [4].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94