Page:NIOSH Manual of Analytical Methods - 3503.pdf/1

 HYDRAZINE

H2NNH2

MW: 32.05

METHOD: 3503, Issue 2

CAS: 302-01-2

3503

RTECS: MU7175000

EVALUATION: FULL

OSHA : 1 ppm (skin) NIOSH: C 0.03 ppm/120 min(suspect carcinogen) ACGIH: 0.1 ppm (skin; suspect carcinogen) (1 ppm = 1.31 mg/m 3 @ NTP)

PROPERTIES:

Issue 1: 15 February 1984 Issue 2: 15 August 1994

liquid; d 1.004 g/mL @ 25 °C; BP 113.5 °C; MP 2 °C; VP 1.92 kPa (14.4 mm Hg; 18,900 ppm) @ 25 °C)

SYNONYMS: diamide; diamine

SAMPLING

MEASUREMENT

SAMPLER:

BUBBLER (15 mL 0.1 M HCl)

TECHNIQUE:

SPECTROPHOTOMETRY, ABSORPTION

FLOW RATE:

0.2 to 1.0 L/min

ANALYTE:

quinoid derivative of p-dimethylaminobenzaldazine [2]

VOL-MIN: -MAX:

7 L @ 1 ppm 100 L

SHIPMENT:

routine

COMPLEXATION: p-dimethylaminobenzaldehyde; stand 30 min; acetic acid

SAMPLE STABILITY:

≥ 6 days @ 25 °C

BLANKS:

2 to 10 field blanks per set

ACCURACY 0.59 to 3.4 mg/m [1] (91-L samples)

BIAS:

625 mL

WAVELENGTH:

480 nm

CALIBRATION:

hydrazine in methanol

RANGE:

9 to 400 µg per sample

PRECISION (Sr):

0.031 [1]

- 0.3%

ˆ ): OVERALL PRECISION (S rT ACCURACY:

FINAL VOLUME:

ESTIMATED LOD: 0.9 µg per sample 3

RANGE STUDIED:

VISIBLE

0.094 [1] ± 17.1%

APPLICABILITY: The working ranges are 0.07 to 3 ppm (0.09 to 4 mg/m 3) for 100-L air samples and 0.45 to 21 ppm (0.6 to 27 mg/m 3) for 15-L air samples. This method is applicable to hydrazine vapor. It has not been tested with aerosol forms. The free base cannot be distinguished from salts, such as hydrazine monohydrochloride and hydrazine sulfate, which are aeros ols.

INTERFERENCES: Methylhydrazine is an interference. Other hydrazines may interfere.

OTHER METHODS: This method is a modification of and replaces Method S237 [2]. Method P&CAM 248 is a gas chromatographic method which can be used for quantitation of hydrazine or substituted hydrazines [3]. Methods S143, S149 and S160 utilize a non-specific colorimetric method for substituted hydrazines [4].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94