Page:NIOSH Manual of Analytical Methods - 3500.pdf/4

 FORMALDEHYDE: METHOD 3500, Issue 2, dated 15 August 1994 - Page 4 of 5 EVALUATION OF METHOD: The method was checked for reproducibility by having three different analysts in three different laboratories analyze standard samples containing between 1 and 20 µg formaldehyde. The results agreed within ± 5% [8]. This method was independently compared with the 2,4,-dinitrophenylhydrazine-coated silica gel method of Beasley et al. [12] over the range of 0.8 to 2.2 ppm formaldehyde and was found to give approximately 25% lower concentrations. In another study comparing this method and the method of Beasley, et al., all three methods were found to be statistically equivalent for loadings from 8.2 to 22.4 µg per sample [13]. The method of Septon and Ku [14] was compared with this method. The slope of the correlation line was 1.09. The concentration range of the comparison was not given. In a study comparing the pararosaniline method [4] and NIOSH P&CAM 125 over the range of 0.021 to 0.5 ppm, the NIOSH method gave better collection efficiency and accuracy [15]. Precision for both methods was equivalent.

REFERENCES: [1] Kennedy, E. R., D. L. Smith, and C. L. Geraci, Jr. "Field Evaluation of Sampling and Analytical Methods for Formaldehyde," Chapter 11 in Advances in Chemistry Series No. 210 (Formaldehyde: Analytical Chemistry and Toxicology ), American Chemical Society (Washington, D.C., 1985). [2] Formaldehyde, NIOSH Method No. S327 Failure Report, NIOSH/OSHA Standards Completion Program Contract Report, Cincinnati, Ohio (1976). [3] User check, Southern Research Institute, NIOSH Sequence #3500 (unpublished, November 10, 1983). [4] Miksch, R. R., D. W. Anthon, L. Z. Fanning, C. D. Hollowell, K. Revzan and J. G. Glanville, Anal. Chem., 53, 2118-2123 (1981) [5] Hakes, D.C., C. D. Johnson and J. S. Marheva. Am. Ind. Hyg. Assoc. J. 45, 274-277 (1984). [6] Sleva, S .F. Determination of Formaldehyde: Chromotropic Acid Method, PHS Publication 999-AP-11, H-1 (1965). [7] NIOSH Manual of Analytical Methods, 2nd ed., V.1, P&CAM 125, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 77-157-A (1977). [8] "Methods of Air Sampling and Analysis," Method 111, Intersociety Committee for a Manual of Methods of Air Sampling and Analysis, American Public Health Association, Washington, DC, 194-198 (1972) and M.Katz, ed., "Methods of Air Sampling and Analysis," 2nd ed., Intersociety Committee on Methods of Air Sampling and Analysis, American Public Health Association, Washington, DC, Method 116, 303-307 (1977). [9] Kennedy, E. R., A. W. Teass, and Y. T. Gagnon. Industrial Hygiene Sampling and Analytical Methods for Formaldehyde. ACS Advances in Chemistry Series 210: Analyt. Chem. Toxicol. (1985). [10] NIOSH/OSHA Occupational Health Guidelines for Occupational Hazards, U.S. Department of Health and Human Services, Publ. (NIOSH) 81-123 (1981), available as GPO Stock #017-03300337-8 from Superintendent of Documents, Washington, DC 20402. [11] Dollberg, D. D., D. L. Smith and D. G. Tharr. App. Ind. Hyg., 1, F44-F46 (1986). [12] Beasley, R. K., C. E. Hoffmann, M. L. Reuppel and J. W. Worley. Anal. Chem., 52, 1110-1114 (1980). [13] Kennedy, E. R., D. L. Smith, M. Bolyard and R. Hornung. Further Adventures in Formaldehyde Sampling and Analysis, Poster Session at 1982 American Industrial Hygiene Conference, Cincinnati, OH (1982). [14] Septon J. C. and J. C. Ku. Am. Ind. Hyg. Assoc. J., 43, 845-852 (1982) [15] Petreas, M., S. Twiss, D. Pon and M. Imada. Am. Ind. Hyg. Assoc., J., 47, 276-280 (1986)

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94