Page:NIOSH Manual of Analytical Methods - 2558.pdf/1

 ACETOIN C4 H8 O2

MW: 88.11

METHOD: 2558, Issue 1

2558

CAS: 513-86-0

RTECS: EL8790000

EVALUATION: PARTIAL

PROPERTIES:

OSHA : None NIOSH: None ACGIH: None

Issue 1: 15 March 2003

liquid, solid (dimer); d= 0.9972 g/mL @ 20 °C; BP= 148 °C; FP = 50°C; MP= 15°C; Miscible in water and alcohol

SYNONYMS: 3-Hydroxy-2-butanone, 2,3-butanolone, acetyl methyl carbinol, dimethylketol

SAMPLING SAMPLER:

Anasorb CMS Solid Sorbent Tubes (150/75 mg)

FLOW RATE:

0.01 to 0.2 L/min

VOL-MIN: -MAX :

1L 10 L

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

Acetoin

DESORPTION:

1 mL of acetone/methanol (95:5) on rotary mixer for 1.5 hours

INJECTION VOLUME:

1µL

225°C 250°C 35°C (hold 3 min) to 200°C (6°C/min)

SAMPLE STABILITY:

30 days @ 5°C

TEMPERATURE -INJECTION: -DETECTOR: -COLUMN:

BLANKS:

10% of field samples

CARRIER GAS:

He (2.8 mL/min)

COLUMN:

Capillary, fused silica, 30 m x 0.32-mm ID; 1-µm film, Stabilwax-DA or equivalent

CALIBRATION:

Standard solutions in acetoin in acetone/methanol (95:5) solvent

RANGE:

3 to 378 µg

SHIPMENT:

Ship cold (5°C) and store in dark

ACCURACY RANGE STUDIED:

Not Determined

BIAS:

Not Determined

OVERALL PRECISION (Ö r T ): Not Determined ACCURACY:

Not Determined

ESTIMATED LOD: 1.0 µg PRECISION ( þ r ):

0.008

APPLICABILITY: The working range for acetoin was 0.6 to 75.6 mg/m3 for a 5 L air sample.

INTERFERENCES: Any compounds with similar retention times to acetoin.

OTHER METHODS: None determined.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition