Page:NIOSH Manual of Analytical Methods - 2553.pdf/1

 KETONES II FORMULAS: TABLE 1

MW: TABLE 1

METHOD: 2553, Issue 1

CAS: TABLE 1

EVALUATION: PARTIAL

PROPERTIES:

OSHA : Table 1 NIOSH: Table 1 ACGIH: Table 1

COMPOUNDS/ SYNONYMS:

2553

(1) 2-Heptanone: Methyl-n-amyl ketone (2) 3-Heptanone: Ethyl butyl ketone (3) Mesityl oxide: 4-Methyl-3-penten-2-one

SOLID SORBENT TUBE (Anasorb CMS, 150/75 mg) [1]

FLOW RATE:

0.01 to 0.2 L/min

VOL-MIN: -MAX:

1L 25 L

SHIPMENT:

Routine

SAMPLE STABILITY:

30 days @ 5°C [1]

BLANKS:

10% of samples ACCURACY

RANGE STUDIED:

Not Determined.

BIAS:

Not Determined.

OVERALL PRECISION ( Ö r T ):

Not Determined.

ACCURACY:

Not Determined.

Issue 1: 15 March 2003

Table 1

(4) 5-Methyl-3-heptanone: Ethyl amyl ketone (5) Camphor: 2-Camphanone, Gum Camphor

SAMPLING SAMPLER:

RTECS: TABLE 1

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

Table 1

DESORPTION:

1 mL of 2% isopropanol in CS 2 with agitation [1]

INJECTION VOLUME:

1 µL

TEMPERATURE -INJECTION: -DETECTOR: -COLUMN:

225°C [1] 300°C [1] 55°C (3 min hold) to 190°C (8°C/min) [1]

CARRIER GAS:

Helium (4.8 mL/min) [1]

COLUMN:

Capillary, fused silica, 30-m x 0.32-mm ID; 1.00 µm film crossbond trifluoropropylmethyl polysiloxane or equivalent [1]

CALIBRATION:

Solutions of analytes in desorption solvent

RANGE:

See Table 2 [1]

ESTIMATED LOD: See Table 2 [1] PRECISION ( þ r ):

See Table 2 [1]

APPLICABILITY: For a 10-L air sample, the working range for 2-heptanone is 0.86 to 24.8 ppm (4.0 to 121 mg/m3 ); for 3heptanone is 0.43 to 12.9 ppm (2.0 to 60.3 mg/m3 ); for mesityl oxide is 0.22 to 6.89 ppm (0.9 to 22.6 mg/m3 ); for 5-methyl-3heptanone is 0.21 to 6.29 ppm (1.1 to 33.0 mg/m3 ); and for camphor is 0.14 to 4.84 ppm (0.9 to 30.2 mg/m3 ) [1].

INTERFERENCES:

Any compound having the same retention times as the analytes of interest.

OTHER METHODS: This method was developed as part of an update of NIOSH Method 1301 (Issue 2, 15 August 1994) [2] which combined the NIOSH Methods: S10, S12, S13, S15, and S16 from the 2nd edition of the NIOSH Manual of Analytical Methods [3,4]. Improvements included: lower LOD/LOQ values, improved DE recovery results (at lower levels) by using Anasorb CMS and 2% IPA in CS 2, a 30 day storage stability study, and the replacement of the packed column with a Rtx-200 fused silica capillary column.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition