Page:NIOSH Manual of Analytical Methods - 2522.pdf/4

 NITROSAMINES: METHOD 2522, Issue 2, dated 15 August 1994 - Page 4 of 4 [1] [2] [3] [4]

Roundbehler, D. and Fajen J. N-Nitroso Compounds in the Factory Environment, NIOSH contract #210-77-0100 (1977). Foley, D. NIOSH/MRSB Method Development Efforts, Backup Data Report and Analysis for Nitrosamines, NIOSH, (Unpublished, 1983-1988). NIOSH Manual of Analytical Methods, 2nd ed., V. 1, P&CAM 252, U.S. Department of Health Education, and Welfare, Publ. (NIOSH) 77-157-A (1977). Ibid., V.5, P&CAM 299, NIOSH Publ. 79-141 (1979).

METHOD WRITTEN BY: G. David Foley, NIOSH/DPSE.

Table 1: General Information Compounds (Synonyms)

Formula

MW

Properties

N-nitrosodimethylamine (N-Methyl- N-nitrosomethanamine; dimethylnitrosamine; DMN; DMNA; CAS #62-75-9) RTECS: IQ0525000

(CH 3)2N-N=O

74.1

liquid; d 1.00 g/mL @ 20 °C; BP 151 °C; VP 0.36 kPa (2.7 mm Hg) @ 20 °C

N-nitrosodiethylamine (N-Ethyl-N-nitrosoethanamine; diethylnitrosamine; DEN; DENA; CAS #55-18-5) RTECS: IA3500000

(C2H5)2N-N=O

102.1

liquid, d 0.94 g/mL @ 20 °C; BP 175 °C; VP 0.1 kPa (0.86 mm Hg) @ 20 °C

N-nitrosodipropylamine (N-Propyl- N-nitrosopropylamine DPN; DPNA; CAS #621-64-7) RTECS: JL9700000

(C3H7)2N-N=0

130.2

liquid; d 0.916 g mL/@ 20 °C; BP 194.5 °C; VP 11 Pa (0.085 mm Hg) @ 20 °C

N-nitrosodibutylamine (N-Butyl-N-nitrosobutylamine; dibutylnitrosamine; CAS #924-16-3) RTECS: EJ4025000

(C4H9)2N-N=O

158.3

liquid; d 9.901 g/mL @ 20 °C; BP 116 °C @ 14 mm Hg, VP 4 Pa (0.03 mm Hg) @ 20 °C

N-nitrosomorpholine (NMOR; 4-Nitrosomorpholine; MORNA; CAS #59-89-2) RTECS: QE7525000

C 4H 8N 2O 2

116.1

liquid/crystals; d unknown; BP 225 °C; MP 29 °C; VP unknown

N-nitrosopiperidine (N-NPIP; PIPNA; NPIP; CAS #100-75-4) RTECS: TN2100000

(CH 2)5N-N=0

114.2

liquid; d 1.063 @ 19 °C; BP 217 °C @ 720 mm Hg; VP unknown

N-nitrosopyrrolidine (N-NPyr; NPYR, PYRNA; 1-Nitrosopynolodine; CAS #930-55-2) RTECS: UY1575000

C4H8N-N=0

100.1

liquid; d 1.09 g/mL @ 20 °C; BP 214 °C; VP 10 Pa (0.072 mm Hg) @ 20 °C

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94