Page:NIOSH Manual of Analytical Methods - 2012.pdf/1

 n-BUTYLAMINE

CH3(CH2)3NH2

MW: 73.16

METHOD: 2012, Issue 1

2012

CAS: 109-73-9

RTECS: EO2975000

EVALUATION: FULL

OSHA : 5 ppm (skin) ceiling NIOSH: 5 ppm (skin) ceiling ACGIH: 5 ppm (skin) ceiling (1 ppm = 2.99 mg/m 3 @ NTP)

Issue 1: 15 August 1994

PROPERTIES: liquid, ammoniacal odor; MP -49 °C; BP 77.8 °C; d = 0.7327 g/mL @ 25 °C; VP 10.9 kPa (82 mm Hg) @ 20 °C; vapor density 2.5 (air = 1)

SYNONYMS: butylamine, 1-aminobutane, NBA

SAMPLING SAMPLER:

MEASUREMENT

SOLID SORBENT TUBE (sulfuric acid-treated silica gel tube 150 mg/75 mg)

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

n-butylamine

FLOW RATE:

0.01 to 1.0 L/min

EXTRACTION:

1 mL 50% methanol; neutralize a 500µL aliquot with 1 N KOH

VOL-MIN: -MAX:

2L 100 L

INJECTION VOLUME:

SHIPMENT:

routine

SAMPLE STABILITY:

TEMPERATURE-INJECTOR: -DETECTOR: -COLUMN:

at least 7 days @ 25 °C

BLANKS:

2 to 10 field blanks per set

ACCURACY RANGE STUDIED:

8.09 to 35.5 mg/m 3 [1] (15-L samples)

BIAS:

- 5.1%

5 µL 175 °C 195 °C 90 °C

CARRIER GAS:

N 2, 20 mL/min

COLUMN:

4% Carbowax 20M + 0.8% KOH on 60/80 mesh Carbopack B, 6 ft x 1/4"-O.D.

CALIBRATION:

standard solutions of butylamine in aqueous methanol

RANGE:

0.03 to 1 mg per sample [1]

ESTIMATED LOD: 0.012 mg per sample [2]

ˆ ): 0.092 [1] OVERALL PRECISION (S rT ACCURACY:

± 23.1%

PRECISION (Sr):

0.0490 [1]

APPLICABILITY: The working range is 0.7 to 144 ppm (2 to 430 mg/m 3) for a 15-L air sample. Using a nitrogen-specific detector instead of a FID will greatly increase sensitivity. This alternate detector has been used for amines with a 30-m x 0.25- mm x 0.25µm film DB-5 (5% methyl, phenyl-50% dimethyl-polysiloxane) fused-silica capillary column with a liner packed with KOH-co ated glass wool.

INTERFERENCES: Both concentrated sulfuric acid and silica gel are desiccants, so in sampling atmospheres above 60% relative humidity the sorbent tube may have lowered capacity.[1]

OTHER METHODS: This revises Method S138 [3]. Method 2010 for aliphatic amines may also be used for determination of nbutylamine.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94