Page:NIOSH Manual of Analytical Methods - 2007.pdf/4

 AMINOETHANOL COMPOUNDS I: METHOD 2007, Issue 2, dated 15 August 1994 - Page 4 of 5 CALCULATIONS: 16.

17.

Determine the mass, mg (corrected for DE) of analyte found in the sample front (W f) and back (W b) sorbent sections, and in the average media blank front (B f) and back (B b) sorbent sections. NOTE: If W b > W f/10, report breakthrough and possible sample loss. Calculate concentration, C, of analyte in the air volume sampled, V (L):

EVALUATION OF METHOD: All three compounds were evaluated under Method P&CAM 270 using a smaller bed of silica gel (front = 150 mg; back = 150 mg) than given above [3]. Desorption efficiencies for 0.1 mg analyte were found to be 0.97 for 2-aminoethanol, 0.85 for 2-diethylaminoethanol, and 0.93 for 2-dibutylaminoethanol [3]. Only 2-diethylaminoethanol was evaluated under Method S140 using the suggested sorbent tube. In all cases, laboratory testing was performed with spiked samples and generated atmosphere [1,2,6]. All analytes were stable on silica gel up to four weeks when stabilized with acid. Results were:

Compound

Method

Range Studied (mg/m 3)

2-aminoethanol 2-dibutylaminoethanol 2-diethylaminoethanol

P&CAM 270 [3] P&CAM 270 [3] S140 [4]

30.4 to 63.6 unknown 25 to 113

Sample size (L) 30 unknown 24

Precision Measurement (Sr) Overall (SˆrT) <0.070 unknown 0.026

0.057 unknown 0.056

Method S140 [4] was issued on January 19, 1979, and validated over the range 25 to 113 mg/m 3 at 23 °C and 762 mm Hg using 24-L samples [2,7]. Coast Engineering Laboratory 40/60 mesh silica gel was the collecting medium. Average recovery was 97.1%, representing a non-significant bias. The concentration of 2-diethylaminoethanol was independently verified using midget bubblers containing 15 mL 2% HCl. Desorption efficiency was 0.964 in the range 0.6 to 2.3 mg per sample. Breakthrough (5% on back section) was not achieved after 5.3 h when sampling an atmosphere containing 88 mg/m 3 2-diethylaminoethanol at 0.2 L/min at 82% relative humidity.

REFERENCES: [1]

[2] [3] [4] [5]

[6]

Wood, G. O. and J. W. Nickols. Development of Air-Monitoring Techniques Using Solid Sorbents, October 1, 1976 - December 31, 1977, Progress Report LA-7295-PR, Los Alamos Scientific Laboratory, Los Alamos, NM, NIOSH IA-77-12 (1978). Backup Data Report No. S140, prepared under NIOSH Contract 210-76-0123 (NIOSH, unpublished, 1979); Report on NIOSH Sequence #5162 (unpublished, April 2, 1986). NIOSH Manual of Analytical Methods, 2nd ed., Vol. 4, P&CAM 270, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 78-175 (1978). Ibid., Vol. 5, S140, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 79-141 (1979). NIOSH/OSHA Occupational Health Guidelines for Chemical Hazards, Diethylaminoethanol and Ethanolamine, U.S. Department of Health and Human Services, Publ. (NIOSH) 81-123 (1981), available as GPO Stock #017-033-00337-8 from Superintendent of Documents, Washington, DC 20402. Wood, G. O., R. G. Anderson and J. W. Nickols. Sampling and Analysis of Aminoethanols in Air, Report LA-UR-77-1398, Industrial Hygiene Group, Los Alamos Scientific Laboratory, Los

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94