Page:NIOSH Manual of Analytical Methods - 2002.pdf/1

 AMINES, AROMATIC

Table 1

MW: Table 1

METHOD: 2002, Issue 2

CAS: Table 2

Issue 1: 15 May 1985 Issue 2: 15 August 1994

PROPERTIES: Table 1

aniline: benzenamine; aminobenzene; phenylamine o-toluidine: 2-aminotoluene 2,4-xylidine: 2,4-dimethylaniline; dimethylaminobenzene N,N-dimethyl- p-toluidine: p-dimethylaminotoluene N,N-dimethylaniline: N,N-dimethylbenzeneamine SAMPLING

SAMPLER:

RTECS: Table 2

EVALUATION: FULL (1-3); PARTIAL (4,5)

OSHA : Table 2 NIOSH: Table 2 ACGIH: Table 2 SYNONYMS: (1) (2) (3) (4) (5)

2002

SOLID SORBENT TUBE (silica gel, 150 mg/75 mg)

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

amines listed above

DESORPTION:

1 mL 95% ethanol; 1 h in ultrasonic bath

INJECTION VOLUME:

5 µL

CARRIER GAS:

N 2 or He, 25 mL/min

(1), (2), and (3) stable for ≥ 7 days [1]; stability data not available for (4) and (5)

COLUMN:

stainless steel, 0.6 m x 3-mm OD, packed with 80/100 mesh Chromosorb 103

2 to 10 field blanks per set

CALIBRATION:

standard solutions of analytes in 95% ethanol

RANGE:

0.1 to 3 mg per sample

FLOW RATE: Table 2 VOL-MIN: -MAX:

Table 2 Table 2

SHIPMENT:

routine

SAMPLE STABILITY:

BLANKS:

ACCURACY RANGE STUDIED:

see EVALUATION OF METHOD

BIAS:

see EVALUATION OF METHOD

ˆ rT): see EVALUATION OF METHOD OVERALL PRECISION (S ACCURACY:

ESTIMATED LOD: 0.01 mg per sample [2]; not determined for (3) PRECISION (Sr):

see EVALUATION OF METHOD

see EVALUATION OF METHOD

APPLICABILITY: See Table 2 for working ranges. A modification of this method has been used for aniline and o-toluidine at a vulcanized rubber manufacturing plant [2]. Applicability of this method for simultaneous determination of the analytes has not been investigated. A nitrogen-specific GC detector instead of an FID will greatly increase sensitivity.

INTERFERENCES: None known. Silica gel has reduced capacity for organic compounds at high humidity.

OTHER METHODS: This combines Methods S162 (xylidine) [3], S164 (dimethylaniline) [3], S168 ( o-toluidine) [3], S310 (aniline) [3], P&CAM 280 (N,N-dimethyl-p-toluidine) [4], and P&CAM 168 (aromatic amines) [5,6].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94