Page:NIOSH Manual of Analytical Methods - 1618.pdf/1

 ISOPROPYL ETHER ((CH3)2CH)2 O

MW: 102.18

METHOD: 1618, Issue 2

1618

CAS: 108-20-3

RTECS: TZ425000

EVALUATION: PARTIAL

OSHA : 500 ppm NIOSH: 500 ppm ACGIH: 250 ppm; STEL 310 ppm

Issue 1: 15 August 1994 Issue 2: 15 March 2003

PROPERTIES: liquid; 0.725 g/mL @ 20°C; BP 67.5°C; VP 15.9 kPa (119 mm Hg, 15.7% v/v) @ 20°C; explosive range 1.4 to 7.9% v/v in air

(1 ppm = 4.18 mg/m3 @ NTP) Synonyms: diisopropyl ether; 2-isopropoxypropane; 2,2'-oxybispropane

SAMPLING SAMPLER:

Solid Sorbent Tube (coconut shell charcoal; 100 mg/50 mg)

FLOW RATE:

0.01 to 0.05 L/min

VOL-MIN: -MAX:

0.1 L @ 500 ppm 3L

SHIPMENT:

Routine

SAMPLE STABILITY:

30 days @ 5 °C

BLANKS:

2 to 10 field blanks per set

ACCURACY RANGE STUDIED:

992 to 4260 mg/m3 [2] (3-L samples)

BIAS:

2.2%

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

Isopropyl ether

DESORPTION:

1 mL CS2 ; stand 30 min

INJECTION VOLUME:

1 µL

TEMPERATURES -INJECTION: 250 °C -DETECTOR: 300 °C -COLUMN: 35 °C (1 min) - 150 °C ramp (10 °C /min) CARRIER GAS:

Helium (1-2 mL/min)

COLUMN:

Capillary, fused silica, 30-m x 0.32-mm ID; 3:m film 100% dimethyl siloxane

CALIBRATION:

Solutions of analyte in CS 2

RANGE:

2 to 651 µg per sample (capillary column); 1000 to 12000 µg per sample (packed column)

OVERALL PRECISION (Ö r T ): 0.056 ACCURACY:

±12.0%

ESTIMATED LOD: 0.2 µg per sample [1] PRECISION ( þ r ):

0.014 [1]

APPLICABILITY: The working range is 3 to 1170 ppm (16 to 4900 mg/m3 ) for a 3-L air sample [1]. The sorbent's capacity for the analyte has not been determined under conditions of high relative humidity [2].

INTERFERENCES: Any compound that has a similar retention time under these analytical conditions.

OTHER METHODS: This method is based on and supercedes S368 [3] and NMAM 1618 (Issue 1) [5].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition