Page:NIOSH Manual of Analytical Methods - 1613.pdf/1

 PYRIDINE

C5H5N

MW: 79.10

METHOD: 1613, Issue 2

CAS: 110-86-1

1613

RTECS: UR8400000

EVALUATION: FULL

OSHA : 5 ppm NIOSH: 5 ppm; Group III Pesticide ACGIH: 5 ppm (1 ppm = 3.23 mg/m 3 @ NTP)

PROPERTIES:

Issue 1: 15 August 1987 Issue 2: 15 August 1994

liquid; d 0.982 g/mL @ 20 °C; BP 115 °C; MP -42 °C; VP 2.4 kPa (18 mm Hg; 2.4% v/v) @ 20 °C; explosive limits 1.8 to 12.4% v/v in air

SYNONYMS: azine; azabenzene

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

pyridine

FLOW RATE:

0.01 to 1.0 L/min

DESORPTION:

1 mL methylene chloride; stand 30 min

VOL-MIN: -MAX:

18 L 150 L

INJECTION VOLUME:

5 µL

SHIPMENT:

routine

SAMPLE STABILITY:

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

not determined

FIELD BLANKS:

2 to 10 field blanks per set

CARRIER GAS:

260 °C 285 °C 140 °C

N 2, 30 mL/min

COLUMN:

3 m x 3-mm OD stainless steel packed with 5% Carbowax 20M on 80/100 mesh acid-washed DMCS Chromosorb W

CALIBRATION:

standard solutions methylene chloride

RANGE:

0.3 to 4.5 mg per sample

ACCURACY RANGE STUDIED:

7.6 to 30 mg/m 3 [1] (100-L samples)

BIAS:

9.2%

ˆ rT): 0.059 [1] OVERALL PRECISION (S ACCURACY:

± 19.8%

of

pyridine

in

ESTIMATED LOD: 0.02 mg per sample [2] PRECISION (Sr):

0.014 @ 0.8 to 3.1 mg per sample [1]

APPLICABILITY: The working range is 1 to 14 ppm (3 to 45 mg/m 3) for a 100-L air sample.

INTERFERENCES: None detected. The chromatographic column or separation may be changed to circumvent interference problems (e.g., 30 m x 0.32-mm capillary column with 1 µm DB-5 at 50 °C [2]).

OTHER METHODS: This revises Method S161 [3].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94