Page:NIOSH Manual of Analytical Methods - 1612.pdf/1

 PROPYLENE OXIDE

C3H6O

MW: 58.08

METHOD: 1612, Issue 2

CAS: 75-56-9

1612

RTECS: TZ2975000

EVALUATION: PARTIAL

OSHA : 100 ppm NIOSH: lowest feasible (carcinogen); Group I Pesticide ACGIH: 20 ppm (1 ppm = 2.37 mg/m 3 @ NTP)

PROPERTIES:

Issue 1: 15 May 1985 Issue 2: 15 August 1994

liquid; d 0.8287 g/mL @ 20 °C; BP 34 C; MP -104 °C; VP 59 kPa (442 mm Hg; 58% v/v) @ 20 °C; explosive range 2.1 to 37% (v/v) in air

SYNONYMS: 1,2-epoxypropane; methyloxirane

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

propylene oxide

FLOW RATE:

0.01 to 0.2 L/min

DESORPTION:

1 mL CS 2; stand 30 min

VOL-MIN: -MAX:

0.5 L @ 100 ppm 5L

INJECTION VOLUME:

5 µL

SHIPMENT:

refrigerated

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

SAMPLE STABILITY:

not determined

FIELD BLANKS:

2 to 10 field blanks per set

190 °C 255 °C 40 °C, 6 min; 50 °C/min to 250 °C

CARRIER GAS:

N 2, 1 mL/min; makeup 29 mL/min

COLUMN:

30 m x 0.32-mm fused silica capillary column, 1.0-µm DB-5 [2]

CALIBRATION:

propylene oxide in CS 2

RANGE:

0.03 to 3 mg per sample [2]

ACCURACY 121 to 482 mg/m 3 [1] (5-L samples)

RANGE STUDIED: BIAS:

- 1.8%

ESTIMATED LOD: 0.01 mg per sample

ˆ ): 0.085 [1] OVERALL PRECISION (S rT ACCURACY:

± 11.9%

PRECISION (Sr):

0.029 @ 0.6 to 2.4 mg per sample [1]

APPLICABILITY: The working range is 8 to 295 ppm (20 to 700 mg/m 3) for a 5-L air sample [1].

INTERFERENCES: None found.

OTHER METHODS: This revises method S75 [3].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94