Page:NIOSH Manual of Analytical Methods - 1609.pdf/1

 TETRAHYDROFURAN

C4H8O

MW: 72.11

METHOD: 1609, Issue 2

CAS: 109-99-9

1609

RTECS: LU5950000

EVALUATION: PARTIAL

OSHA : 200 ppm NIOSH: 200 ppm; STEL 250 ppm ACGIH: 200 ppm; STEL 250 ppm (1 ppm = 2.95 mg/m 3 @ NTP)

PROPERTIES:

Issue 1: 15 May 1985 Issue 2: 15 August 1994

liquid; MP -108 °C; BP 66 °C; d 0.886 g/mL @ 20 °C; VP 19.3 kPa (145 mm Hg; 19% v/v) @ 20 °C; explosive range 2 to 11.8% v/v in air

SYNONYMS: diethylene oxide; THF

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

FLOW RATE:

0.01 to 0.2 L/min

VOL-MIN: -MAX:

1L 9L

SHIPMENT:

routine

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

tetrahydrofuran

DESORPTION:

0.5 mL CS 2; stand 30 min

INJECTION VOLUME:

5 µL

SAMPLE STABILITY:

not determined

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

BLANKS:

2 to 10 field blanks per set

CARRIER GAS:

N 2, 30 mL/min

COLUMN:

stainless steel, 1.2 m x 6-mm OD, packed with 50/80 mesh Porapak Q

CALIBRATION:

tetrahydrofuran in CS 2

RANGE:

0.5 to 13 mg per sample

ACCURACY RANGE STUDIED:

323 to 1240 mg/m 3 [1] (9-L samples)

BIAS:

- 3.9%

ˆ ): 0.055 [1] OVERALL PRECISION (S rT ACCURACY:

190 °C 250 °C 185 °C

ESTIMATED LOD: 0.05 mg per sample PRECISION (Sr):

0.016 @ 3 to 11.8 mg per sample [1]

± 12.6%

APPLICABILITY: The working range is 100 to 2600 mg/m 3 (34 to 880 ppm) for a 5-L air sample.

INTERFERENCES: High humidity may reduce the breakthrough volume of the charcoal tube. The column specified may not be appropriate for large numbers of samples. CS 2 tends to dissolve some porous polymers. An alternate GC column is 30 m x 0.32mm ID fused silica capillary coated with 0.5 µm DBWAX at 60 °C [2].

OTHER METHODS: This revises Method S78 [3].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94