Page:NIOSH Manual of Analytical Methods - 1608.pdf/1

 GLYCIDOL

C3H6O 2

MW : 74.08

METHOD: 1608, Issue 2

CAS: 556-52-5

1608

RTECS: UB4375000

EVALUATION: FULL

OSHA : 50 ppm NIOSH: 25 ppm ACGIH: 25 ppm (1 ppm = 3.03 mg/m 3 @ NTP)

Issue 1: 15 May 1985 Issue 2: 15 August 1994

PROPERTIES: liquid; d 1.117 g/mL @ 20 °C; BP 167 °C (decomposes); MP - 45 °C; VP 0.12 kPa (0.9 mm Hg); 0.12% v/v) @ 20 °C

SYNONYMS: 2,3-epoxy-1-propanol; 2-(hydroxymethyl)oxirane; oxiranemethanol

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

glycidol

DESORPTION:

0.5-mL tetrahydrofuran; stand 30 min

FLOW RATE: 0.01 to 1 L/min VOL-MIN: -MAX:

5 L @ 150 mg/m 3 100 L

SHIPMENT:

at 4 °C

SAMPLE STABILITY:

at least 7 days @ 4 °C [1]

BLANKS:

2 to 10 field blanks per set

INJECTION VOLUME: 5 µL TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

225 °C 260 °C 155 °C

CARRIER GAS:

N 2, 25 mL/min

COLUMN:

3 m x 2-mm ID stainless steel; 10% FFAP on 100/120 mesh Chromosorb W-HP

CALIBRATION:

glycidol in tetrahydrofuran

RANGE:

0.8 to 22 mg per sample

ACCURACY RANGE STUDIED:

73 to 310 mg/m 3 [2] (50-L samples)

BIAS:

- 2.9%

ˆ rT): 0.080 [1] OVERALL PRECISION (S ACCURACY:

ESTIMATED LOD: not determined PRECISION (Sr):

0.016 [1]

± 13.2%

APPLICABILITY: The working range is 16 to 450 mg/m 3 (5 to 150 ppm) for a 50-L air sample. During sampling, high humidity may greatly decrease the breakthrough volume.

INTERFERENCES: None identified.

OTHER METHODS: This is Method S70 [2] in a revised format.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94