Page:NIOSH Manual of Analytical Methods - 1602.pdf/1

 DIOXANE

C4H8O 2

MW: 88.11

METHOD: 1602, Issue 2

CAS: 123-91-1

1602

RTECS: JG8225000

EVALUATION: FULL

OSHA : 100 ppm (skin) NIOSH: 1 ppm/30 min; carcinogen ACGIH: 25 ppm (skin); carcinogen (1 ppm = 3.60 mg/m 3 @ NTP)

Issue 1: 15 May 1985 Issue 2: 15 August 1994

PROPERTIES: liquid; d 1.0337 g/mL @ 20 °C; BP 101 °C; MP 12 °C VP 3.9 kPa (29 mm Hg; 3.8% v/v) @ 20 °C; explosive range 2 to 22% v/v in air

SYNONYMS: dioxan; p-dioxane; 1,4-diethylene dioxide; diethylene ether

SAMPLING SAMPLER:

MEASUREMENT

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

dioxane

DESORPTION:

1 mL CS 2, 30 min

FLOW RATE: 0.01 to 0.2 L/min VOL-MIN: -MAX: SAMPLE STABILITY:

BLANKS:

0.5 L @ 100 ppm 15 L

INJECTION VOLUME:

>1 week @ 25 °C >6 weeks @ -10 °C

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

2 to 10 field blanks per set

CARRIER GAS:

He, 30 mL/min (60 psig)

COLUMN:

6 m x 3-mm stainless steel packed with 10% FFAP on 80/100 mesh Chromosorb W-HP Chromosorb W-HP

CALIBRATION:

solutions of dioxane in CS 2 with internal standard

RANGE:

0.2 to 7 mg per sample [1,2]

ACCURACY RANGE STUDIED: BIAS:

5 µL 225 °C 250 °C 75 °C

3

157 to 660 mg/m [1] (10-L samples) + 9%

ESTIMATED LOD: 0.01 mg per sample [3]

ˆ ): 0.054 [1] OVERALL PRECISION (S rT ACCURACY:

± 18.7

PRECISION (Sr):

0.017 [1]

APPLICABILITY: The working range is 5.5 to 190 ppm (20 to 700 mg/m 3) for a 10-L air sample.

INTERFERENCES: None known. An alternate GC column is 30 m x 0.32-mm ID fused silica capillary coated with 1 µm DB-5 [3].

OTHER METHODS: This method combines and replaces S360 [4] and P&CAM 127 [5] for dioxane. A similar method appears in the dioxane criteria document [6].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94