Page:NIOSH Manual of Analytical Methods - 1600.pdf/4

 CARBON DISULFIDE: METHOD 1600, Issue 2, dated 15 August 1994 - Page 4 of 4 EVALUATION OF METHOD: This method modifies S248, in that 1 mL toluene (instead of 10 mL benzene) is used to desorb samples, resulting in a better desorption efficiency at low levels and safer working conditions for the analyst [8]. Method S248 [5] was issued on January 30, 1976, and validated over the range 15 to 59 mg/m 3 using a 6-L sample with spiked samplers and atmospheres generated by syringe pump/triple air dilution and verified by total hydrocarbon analyzer [1]. Overall precision, SˆrT, was 0.059 with "found" concentrations 0.8% lower than "true" concentrations for 18 samples tested, representing a non-significant bias. Breakthrough (with drying tube preceding charcoal tube) occurred at 162 min (100% RH, 40 ppm CS 2, 0.2 L/min sampling rate) = 32.4 L; DE (0.28 to 1.12 mg/sample) = 0.86; storage stability (0.56 mg/sample) = 85% recovery after one week at 25 °C. At a 1 L/min sampling rate, breakthrough occurred at 19 L at 100 mg/m 3 [4]. A user check of this method gave an estimated LOD of 0.02 mg CS 2 per sample [2].

REFERENCES: [1] Documentation of the NIOSH Validation Tests, S248, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 77-185 (1977), available as GPO Stock #017-033-00231-2 from Superintendent of Documents, Washington, DC 20402. [2] User check, UBTL, Inc., NIOSH Sequence #3990-L (unpublished, November 9, 1983). [3] Criteria for a Recommended Standard...Occupational Exposure to Carbon Disulfide, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 77-156 (1977), available as GPO Stock #017-033-00231-2 from Superintendent of Documents, Washington, DC 20402. [4] McCammon, C.S., P.M. Quinn and R. Kupel. A Charcoal Sampling Method and a Gas Chromatographic Analytical Procedure for Carbon Disulfide, Am. Ind. Hyg. Assoc. J., 36, 618-624 (1975). [5] NIOSH Manual of Analytical Methods, 2nd ed., Vol. 3, S248, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 77-157-C (1977). [6] Ibid., Vol. 1, P&CAM 179, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) 77-157-A (1977). [7] NIOSH/OSHA Occupational Health Guidelines for Chemical Hazards, U.S. Department of Health and Human Services, Publ. (NIOSH) 81-123, available as GPO Stock #017-033-00337-8 from Superintendent of Documents, Washington, DC 20402. [8] Foley, G. D. NIOSH/DPSE (internal memo, April 17, 1985). [9] Quincoces, C.E. and M.G. Gonzaleg. Characterization of the Flame Photometric Detector in the Sulfur Mode, Chromatographia 20:371 (1985).

METHOD REVISED BY: Mary Lynn Woebkenberg, NIOSH/DPSE; S248 originally validated under NIOSH Contract CDC-99-74-45.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94