Page:NIOSH Manual of Analytical Methods - 1460.pdf/1

 ISOPROPYL ACETATE

MW: 102.14

CH3 COOCH(CH3 )2 METHOD: 1454, Issue 1

1460

CAS: 108-21-4

RTECS: AI4930000

EVALUATION: PARTIAL

OSHA : 250 ppm NIOSH: no REL ACGIH: 250 ppm; STEL 310 ppm

Issue 1: 15 March 2003

PROPERTIES: Colorless liquid; BP 89.4 °C; d 0.87 g/mL @20 °C; miscible in most organic solvents; VP 6.33 kPa (47.5 mm Hg)

(1 ppm = 4.18 mg/m3 @ NTP)

SYNONYMS: 2-Propyl Acetate

SAMPLING

MEASUREMENT

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg, Lot 2000)

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

Isopropyl acetate

FLOW RATE:

0.02 to 0.2 L/min

DESORPTION:

1 mL of carbon disulfide containing 1% methanol

VOL -MIN: -MAX:

0.1 L @ 250 ppm 9L

INJECTION VOLUME: 1 µL

SHIPMENT:

Routine

SAMPLER:

SAMPLE STABILITY:

30 Days @ 5°C

TEMPERATURE -INJECTION: -DETECTOR: -COLUMN:

BLANKS:

2 to 10 field blanks per set

CARRIER GAS:

Helium, 2.8 mL/min

COLUMN:

Capillary, fused silica, 30-m x 0.32mm ID, 1.00 µm film crossbonded® 100% dimethyl polysiloxane or equivalent

CALIBRATION:

Standard solutions of isopropyl acetate in carbon disulfide/ methanol (99:1)

OVERALL PRECISION (Ö rT ): Not Determined

RANGE:

0.6 to 697.6 µg per sample

ACCURACY:

ESTIMATED LOD:

0.2 µg per sample

PRECISION ( þ r ):

0.013

ACCURACY RANGE STUDIED:

Not Studied

BIAS:

Not Determined

Not Determined

250 °C 300 °C 40°C (1 min) to 200°C (10°C/min)

APPLICABILITY: The working range is 0.018 to 20.9 ppm (0.075 to 87.2 mg/m3 ) for an 8-L air sample [3].

INTERFERENCES: None identified.

OTHER METHODS: This method was developed as an update for NMAM 1454, Issue 1 which was based upon NIOSH Method S50 from the 2nd edition of the NIOSH Manual of Analytical Methods [1,2].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition