Page:NIOSH Manual of Analytical Methods - 1457.pdf/1

 ETHYL ACETATE 1457

CH3COOC2H5

MW: 88.10

METHOD: 1457, Issue 1

CAS: 141-78-6 EVALUATION:

OSHA : 400 ppm NIOSH: 400 ppm ACGIH: 400 ppm (1 ppm = 360 mg/m 3 @ NTP)

RTECS: AH5425000

FULL

PROPERTIES:

Issue 1: 15 August 1994

liquid, d = 0.8945 g/mL @ 25 °C; BP = 77 °C; VP = 9.7 kPa (73 mm Hg) @ 20 °C

SYNONYMS: acetic ether; acetic ester; ethyl ethanoate

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

FLOW RATE:

0.01 to 0.2 L/minute

VOL-MIN: -MAX:

0.1 L @ 1400 mg/m 3 10 L

SHIPMENT:

refrigerated

SAMPLE STABILITY:

6 days @ 5 °C [1]

BLANKS:

2 to 10 field blanks per set

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

ethyl acetate

EXTRACTION:

1 mL CS 2

INJECTION VOLUME:

1 µL

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

ACCURACY

RANGE STUDIED:

704 to 2950 mg/m 3 [2] (6-L samples)

BIAS:

-2.1%

250 °C 300 °C 35 °C, 2 min; 10 °C/min to 150 °C

COLUMN:

DB-Wax; 30 m, 0.32-mm ID, 1-µm film thickness

CARRIER GAS:

He, 1 mL/min

MAKEUP GAS:

N 2, 30 mL/min

CALIBRATION:

standard solutions of ethyl acetate in CS 2

RANGE:

1.5 to 1,000 µg per sample [1]

ESTIMATED LOD: 0.5 µg per sample [1]

ˆ ): 0.058 [2] OVERALL PRECISION (S rT ACCURACY:

±11.8%

PRECISION (Sr):

0.019 @ 40.5 to 810 µg per sample [1]

APPLICABILITY: The working range is 0.07 to 790 ppm (0.25 to 2800 mg/m 3) for a 6-L air sample [2]. The method may be adapted for other esters with appropriate changes in chromatographic conditions.

INTERFERENCES: Any compounds with similar retention times.

OTHER METHODS: This revises Method S49 [2]. Improved recovery of analyte may be achieved with the addition of 5% butyl carbitol to the CS 2 desorption procedure [3,4].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94