Page:NIOSH Manual of Analytical Methods - 1403.pdf/1

 ALCOHOLS IV (1) HOCH2 CH2 OCH3 (2) HOCH2 CH2 OCH2 CH3 (3) HOCH2 CH2 O(CH2 )3 CH3

MW: (1) 76.09 (2) 90.12 (3) 118.17

METHOD: 1403, Issue 3

CAS: (1) 109-86-4 RTECS: (1) KL5775000 (2) 110-80-5 (2) KK8050000 (3) 111-76-2 (3) KJ8575000

EVALUATION: FULL

PROPERTIES:

OSHA : See Table 1 NIOSH: See Table 1 ACGIH: See Table 1

SYNONYMS:

1403

Issue 1: 15 August 1990 Issue 3: 15 March 2003

See Table 1

(1) 2-methoxyethanol: methyl cellosolve, ethylene glycol monomethyl ether, EGME (2) 2-ethoxyethanol: cellosolve, ethylene glycol monoethyl ether, EGEE (3) 2-butoxyethanol: butyl cellosolve, ethylene glycol monobutyl ether, EGBE

SAMPLING

MEASUREMENT

SAMPLER:

SOLID SORBENT TUBE (Coconut shell charcoal, 100 mg/50 mg)

FLOW RATE:

0.01 to 0.05 L/min

VOL-MIN: -MAX:

(1) 6L 50 L

SHIPMENT:

Routine

SAMPLE STABILITY:

30 days @ 5°C

BLANKS:

2 to 10 field blanks per set

(2) 1L 6L

(3) 2L 10 L

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

2-methoxyethanol, 2-ethoxyethanol, and 2-butoxyethanol

DESORPTION:

1 mL methylene chloride/methanol (95:5) in an ultrasonic bath for 30 minutes

INJECTION VOLUME:

1 µL

TEMPERATURE -INJECTION: -DETECTOR: -COLUMN:

225°C 300°C 40°C (1 min) - 200°C (12°C/min)

CARRIER GAS:

He, 2.5-3.0 mL/min

COLUMN:

Capillary, fused silica, 30 m x 0.32-mm ID; crossbonded carbowax®-DA or equivalent

CALIBRATION:

Solutions of analytes in desorption solvent

RANGE:

(1) 2 to 387 µg (2) 2 to 373 µg (3) 3 to 361 µg

ACCURACY RANGE STUDIED:

See Table 2.

BIAS:

See Table 2.

OVERALL PRECISION ( Ö r T ):

See Table 2.

ACCURACY:

See Table 2.

ESTIMATED LOD: (1) 0.8 µg/sample (2) 0.7 µg/sample (3) 1.0 µg/sample PRECISION ( þ r ):

(1) 0.024 (2) 0.022 (3) 0.048

APPLICABILITY: The working range for 2-methoxyethanol was 0.095 to 204 ppm (0.33 to 64.5 mg/m3 ) for a 6-L sample volume, for 2-ethoxyethanol was 0.053 to 99 ppm (0.20 to 373 mg/m3 ) for a 1-L sample, and for 2-butoxyethanol was 0.3 to 36.8 ppm (1.5 to 180 mg/m3 ) for a 2-L sample. INTERFERENCES: Any compounds having similar retention times as the analytes of interest.

OTHER METHODS: This method is an improved update of NMAM 1403, issue 2 (15 August 1994) [1 ]. NMAM 1403 (15 August 1994) previously combined and replaced methods S76 [2], S79 [2], and S361 [3]. Other less sensitive methods include OSHA 79 [4] and OSHA 83 [5].

NIOSH Manual of Analytical Methods, Fourth Edition