Page:NIOSH Manual of Analytical Methods - 1301.pdf/1

 KETONES II

TABLE 1

MW: TABLE 1

METHOD: 1301, Issue 2

CAS: Table 1

RTECS: Table 1

EVALUATION: FULL COMPOUNDS (3) and (5): PARTIAL

OSHA/NIOSH/ACGIH: Table 1

COMPOUNDS: (Synonyms in Table 1)

1301

Issue 1: 15 February 1984 Issue 2: 15 August 1994

PROPERTIES: Table 1

(1) camphor (2) mesityl oxide

(3) 5-methyl-3-heptanone (4) methyl-(n-amyl)-ketone

SAMPLING

(5) ethyl butyl ketone

MEASUREMENT

SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

FLOW RATE:

0.01 to 0.2 L/min

VOL-MIN: -MAX:

1L 25 L

SHIPMENT:

routine

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

compounds above

DESORPTION:

1 mL 1% methanol in CS 2; stand in 30 min

INJECTION VOLUME: COLUMN: SAMPLE STABILITY:

unknown

FIELD BLANKS:

2 to 10 field blanks per set

5 µL

stainless steel (3 m x 3-mm ID), 10% FFAP on 80/100 Chromosorb W-AW

TEMPERATURE-INJECTOR: -DETECTOR: -COLUMN:

200 °C 300 °C 100 to 200 °C @ 10 °C/min

CARRIER GAS:

N 2 or He, 30 mL/min

CALIBRATION:

standard solutions of analyte in elution solvent

ACCURACY RANGE STUDIED:

see EVALUATION OF METHOD

BIAS:

see EVALUATION OF METHOD

ˆ rT): OVERALL PRECISION (S METHOD ACCURACY:

see EVALUATION OF

RANGE AND PRECISION:

see EVALUATION OF METHOD

ESTIMATED LOD: 0.05 mg per sample

see EVALUATION OF METHOD

APPLICABILITY: This method was developed to give better desorption than obtainable with carbon disulfide extraction of the charcoal. This method can be used in paint and resin manufacturing plants.

INTERFERENCES: None reported. Alternate columns, e.g., 4 m 10% SP-2100/0.1% Carbowax 1500 on Supelcoport 100/120 or DB-1 fused silica capillary may be used.

OTHER METHODS: This method combines and replaces Methods S10, S12, S13, S15 and S16 [1].

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94