Page:NIOSH Manual of Analytical Methods - 1300.pdf/1

 KETONES I

TABLE 1

MW: TABLE 1

METHOD: 1300, Issue 2

1300

CAS: TABLE 1

EVALUATION: FULL

OSHA/NIOSH/ACGIH: Table 1

COMPOUNDS: (SYNONYMS: Table 1)

Issue 1: 15 May 1989 Issue 2: 15 August 1994

PROPERTIES: Table 1

acetone cyclohexanone diisobutyl ketone

2-hexanone methyl isobutyl ketone 2-pentanone

SAMPLING SAMPLER:

RTECS: TABLE 1

MEASUREMENT

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

FLOW RATE:

0.01 to 0.2 L/min

VOL-MIN: -MAX:

acetone 0.5 L 3L

SHIPMENT:

MIBK must be refrigerated [1]

SAMPLE STABILITY:

unknown

FIELD BLANKS:

2 to 10 field blanks per set

others 1L 10 L

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

compounds above

DESORPTION:

1 mL CS 2; stand 30 min

INJECTION VOLUME:

5 µL

TEMPERATURE-INJECTOR: -DETECTOR: -COLUMN:

250 °C 300 °C 50 °C to 170 °C @ 10°/min

CARRIER GAS:

N 2 or He, 30 mL/min

COLUMN:

glass (3.5 m x 6-mm ID), packed with 10% SP2100 0.1% Carbowax 1500 on Chromosorb WHP

ACCURACY CALIBRATION: ˆ rT), RANGE STUDIED, BIAS, OVERALL PRECISION (S and ACCURACY

standard solutions of analyte in CS 2

RANGE:

0.06 to 10 mg per sample [2]

see EVALUATION OF METHOD

ESTIMATED LOD: 0.02 mg per sample PRECISION (Sr):

see EVALUATION OF METHOD

APPLICABILITY: This is intended as a general method for the ketones listed above. If only certain compounds are of interest, the instrumental conditions can be changed to maximize instrument response for these compounds.

INTERFERENCES: None reported. Alternate columns, e.g., 10% SP-2100 or DB-1 fused silica capillary, can be used.

OTHER METHODS: This method combines and replaces Methods S1, S18, S19 and S20 [3], S178 and S358 [4], and 1300 (dated 2/15/84).

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94