Page:NIOSH Manual of Analytical Methods - 1004.pdf/1

 Rh (ClCH2CH2)2O

METHOD: 1004, Issue 2

CAS: 111-44-4

RTECS: KN0875000

EVALUATION: FULL

OSHA : C 15 ppm (skin) NIOSH: 5 ppm; STEL 10 ppm (skin); carcinogen ACGIH: 5 ppm; STEL 10 ppm (skin); carcinogen (1 ppm = 5.85 mg/m 3 @ NTP)

Issue 1: 15 February 1984 Issue 2: 15 August 1994

PROPERTIES: liquid; d 1.218 g/mL @ 20 °C; BP 178 °C; MP -52 °C; VP 50 Pa (0.4 mm Hg; 530 ppm) @ 20 °C

SYNONYMS: bis(2-chloroethyl) ether; 1,1'-oxybis[2-chloroethane]; 2,2'-dichlorodiethyl ether; sym-dichloroethyl ether

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

dichloroethyl ether

DESORPTION:

1 mL CS 2; stand 30 min

FLOW RATE: 0.01 to 1 L/min VOL-MIN: -MAX:

2 L @ 15 ppm 15 L

SHIPMENT:

routine

INJECTION VOLUME:

5 µL

SAMPLE STABILITY:

at least 7 days @ 25 °C [1]

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

200 - 225 °C 250 - 275 °C 100 - 135 °C

BLANKS:

2 to 10 field blanks per set

CARRIER GAS:

N 2 or He, 30 mL/min

COLUMN:

3 m x 3-mm ID stainless steel; 10% FFAP on 80/100 mesh DMCS Chromosorb W-AW or equivalent

CALIBRATION:

dichloroethyl ether in CS 2

RANGE:

0.15 to 4 mg per sample [2]

ACCURACY RANGE STUDIED: BIAS:

45 to 180 mg/m 3 [1] (15-L samples) - 7.61%

ESTIMATED LOD: 0.01 mg per sample [3]

ˆ ): 0.059 [1] OVERALL PRECISION (S rT ACCURACY:

± 15.7%

PRECISION (Sr):

0.007 [1]

APPLICABILITY: The working range is 1.7 to 46 ppm (10 to 270 mg/m 3) for a 15-L air sample. This method may be used for simultaneous analysis of two or more analytes by changing the chromatographic conditions (e.g., temperature programming). High humidity during sampling will greatly reduce breakthrough volume.

INTERFERENCES: None identified. Alternate columns, e.g., 10% SP-1000 on 80/100 mesh Supelcoport, SP-2100 with 0.1% Carbowax 1500 or DB-1 fused silica capillary column may be used.

OTHER METHODS: This is Method S357 [2] in a revised format.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94