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 Adapted from Kleinman and Horstman [1982].

ventilation, high temperature, and/or low humidity might play a role in the clinical expression of CCP effects.

Pryor et al. 1983. In response to a request for a NIOSH Health Hazard Evaluation, Pryor et al. [1983] investigated complaints of respiratory, eye, and skin irritation and one case of thrombocytopenia at a Colorado municipal court house. A questionnaire was administered to eight employees who worked in an area with intensive storage and use of CCP forms and also to eight others who worked in an area with little CCP contact. The CCP storage was immediately next to 2- and 4-inch pipes carrying hot water during the winter for heating the building; these pipes were believed to be causing increased emissions from the CCP. Heating CCP paper samples in the NIOSH laboratory produced formaldehyde and also substituted biphenyls and terphenyls typical of CCP. However, air samples taken in the office at various times during the months of December and March identified only formaldehyde. CCP-exposed workers during the month of April had somewhat higher prevalences of eye, nasal, and throat complaints (ranging from 25% to 75%) than non-CCP-exposed workers, whose symptoms ranged from 0% to 50%. However, small numbers precluded a statistical test.

Olsen and Merck 1985. Olsen and Morck [1985] administered a questionnaire and physical exams to the 129 workers at two Danish form-printing shops. The authors confirmed complaints that the CCP-exposed parts of the skin exhibited "heavy erythema, combined with irritative itching, vesicles, and wounds together with more chronic changes with lichenification, furrows, and chaps." The frequency of symptoms increased signiﬁcantly (P<0.01) with the volume of CCP handling (see Table 4-9).

Omland et al. 1993. Omland et al. [1993] investigated the extent to which handling large amounts of CCP caused skin and mucous