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 1 1 o Of the manifefl Signs Applications would ailwage it, there was commonly Danger of a Mortification from fo great a Concourfe of peftilential Particles to- gether; and once I remember a Veficle to change into a Carbuncle, from the continued Acceilion to it of frefh morbifick Poifon. WE come now in Courfe to fpeak of Buboes, which were hard and painful Tumours, with Inflammation and Gathering upon the Glands, behind the Ears, Arm-Pits, or Groin. THESE Tumors immediately upon Sei- zure are found fo hard, that they will not at all give Way to the Touch. In fome theie were moveable, and in others fixed :, but after fome Time, this great Tenfion remitted; and it was common to prognofHcate the Event of the Diftemper from their fudden or flow In- creafe, and from their genuine or untoward Suppuration, as alfo from the Degrees of Vi- rulence in their Contents. THE Groans and unfeigned Tears of the Sick too plainly exprefTed the Aggravations of their Miferies, and fbme feemed even to drown their Senfe of Pain with their Com- plainings ; and this Intenfenefs of Pain can- not be a Wonder to any, who duly confider either