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Responsible for the onboard navigational software and for maintenance of the Orbiter's navigational state, known as the state vector.

Also known as “TRAJ," this operator aids the FDO during dynamic flight phases and is responsible for maintaining the trajectory processors in the MCC and for trajectory inputs made to the Mission Operations Computer.

Responsible for all life support systems, cabin pressure, thermal control and supply and waste water management; manages consumables such as oxygen and hydrogen.

{{ul|Electrical Generation and Illumination Officer {EGIL)}}

Responsible for power management, fuel cell operation, vehicle lighting and the master caution and warning system.

Coordinates all payload activities; serves as principal interface with remote payload operations facilities.

Responsible for all onboard mass memory and data processing hardware; monitors primary and backup flight software systems;, manages operating routines and multi-computer configurations.

Manages the reaction control and orbital maneuvering thrusters during all phases of flight; monitors fuel usage and storage tank status; calculates optimal sequences for thruster firings.

Monitors main engine and solid rocket booster performance during ascent phase.

Responsible for all inertial navigational systems hardware such as star trackers, radar altimeters and the inertial