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240 Honorius was condemned as a heretic by the sixth œcumenical council, as we shall shortly see.

After the publication of the of Heraclius, the discussions upon the two operations and two wills assumed greater proportions. The whole East was filled with them. Many bishops declared against the new doctrine, and appealed to the West, in the person of the Bishop of Rome, to sustain the Catholic faith. Pyrrhus, having abandoned his see, was succeeded by Paul, who wrote letters of communion to Theodore, then Bishop of Rome. Theodore replied, praising the orthodoxy of Paul's faith, but expressing surprise that he had not condemned the of Heraclius. Yet he himself did not dare to censure that document openly; he ought, therefore, to have understood why Paul, who was then at Constantinople, had not solemnly condemned it. In his answer, Theodore urged that Pyrrhus, Paul's predecessor, must be canonically deposed, or be sent to Rome to be judged. This opinion was not followed. But Pyrrhus himself, having been proved to be in errour by the monk Maximus of Constantinople, asked to go to Rome, where he was received with all honours due to his title of ex-Patriarch, by Theodore, to whom he intrusted a perfectly orthodox confession of faith.

Rome took advantage of the occasions offered by Monothelism to enlarge her authority. The two Patriarchs of Constantinople and Alexandria having declared in favour of the new doctrine, all those who were orthodox in the East had occasion to turn to the Patriarch of Rome and write to him as the bulwark of the faith which was threatened throughout the East. At such a time the title of successor of St. Peter was not withheld from him, and some bishops went so far as to trace back to that Apostle the authority of the Roman see. This flattered the tendencies which were destined to be daily more and more developed at Rome.