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Rh Brown-Séquard, before the physicians of Brooklyn, I heard him give the following case: A youth (fourteen years old) went to bed perfectly sane, nor had he ever had a symptom of insanity. The next morning when he arose and stepped upon the floor he became a maniac. With great difficulty he was replaced upon the bed, and the moment he touched it he was sane. During the morning he made several attempts to rise, always with the same result. A physician was called, who in his account of the case says: "When sitting up in his bed he drew on his stockings; but on putting his feet on the floor and standing up, his countenance instantly changed, the jaw became violently convulsed, etc. He was pushed back on the bed, was at once calm, looked surprised, and asked what was the matter. Inquiry showed that he had been fishing the preceding day, but had met with no accident. His legs were examined minutely, but nothing unusual was seen; but, says the physician, "On holding up the right great toe with my finger and thumb to examine the sole of that foot, the leg was drawn up and the muscles of the jaws were suddenly convulsed, and on releasing the toe these effects instantly ceased." After further experiment, an irritated point, so small as to be scarcely visible, was taken away by the cutting of a piece of skin, and "the strange sensation was gone and never returned."