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 more whirl'd or brandish'd be put into a more direct Motion) that may give it a peculiar kind of grating or other action upon the nervous and fibrous parts of the body. These, I say, and other suspicious that have sometimes come into my thoughts, I must not stay to examine; but shall now rather offer to Consideration, Whether, since some parts of the humane body are very differing from others in their structure and internal Constitution; and since also some Agents may abound in Corpuscles of differing shapes, bulks, and motions, the same Medicine may not in reference to the same humane body be potentially cold or potentially hot, according as 'tis applied; or perhaps may, upon one or both of the accounts newly mentioned, be cold in reference to one part of the body, and hot in reference to the other. And these effects need not be always ascrib'd to the meer and immediate action of the Corpuscles of the Medicine, but