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Later, Salmon, in The New London Dispensatory, praises the remedy foxglove in no measured terms. Digitalis was first brought prominently under the notice of the medical profession by Dr &quot;W. Withering, who, in his Account of the Foxglove (1785), gave details of upwards of 200 cases, chiefly dropsical, in which it was used. Having become acquainted with the drug in 1775 as an ingredient in a Shropshire family receipt for the cure of dropsy, he began to administer it as a diuretic, but at first in doses too large ; for, &quot; misled by reasoning from the effect of the squills, which generally acts best upon the kidneys when it excites nausea,&quot; he sought to produce the same effect by foxglove. Further experience, however, convinced him &quot;that its diuretic effects do not at all depend upon its exciting nausea or vomiting ; &quot; and that often the urinary discharge may be checked when the dose is imprudently urged so as to occasion sickness. He moreover observed that in cases where the drug produced purging it was inefficacious unless combined with small doses of opium, B-O as to restrain its actioa on the bowels. Withering seldom found it to succeed in men of great natural strength, tense fibre, warm skin, and florid complexion, or in those with a tight and cordy pulse. He recommended digitalis &quot; in every species of dropsy, except the encysted;&quot; and lie was of opinion that it might bo made subservient to the cure of diseases unconnected with dropsy, and that its power over the motion of the heart, to a degree unobserved by him in any other medicine, might be turned to good account by the physician.

1em 1em  DIGNE, the chief town of the department of Basses- Alpes, in France, about 70 miles north-east of Marseilles, in 44 5 32&quot; N. lat. and 6 14 G&quot; E. long. It is built on a spur of the mountains jutting out into a gorge traversed by the Ble onne, which in winter is a formidable torrent, but in summer is almost dry ; and the neighbourhood is rich in orchards, which have long made the town famous in France for its preserved fruits and confections. The streets are narrow and tortuous, with the exception of the Boulevard Gassendi, at the upper end of which is a public garden, with a statue of the philosopher, who was born in the neighbouring village of Chantercier. The cathedral within the town is a buildingof very hybrid architecture, and is of less importance than the cathedral of Notre Dame, in the vicinity, which dates from the 12th century, and id numbered among the historic monuments of France. The thermal springs are not in much repute, and the bathing establishment is in a state of decay. Digne is identified with Dinia, the capital of the Avantici and Bodiontici. It early became an ecclesiastical see, and its bishops acquired the secular rank of barons of Lauzieres. In the 16th century it suffered on four separate occasions from the Huguenot soldiery ; and in modern history it is known as the place from which Napoleon issued his proclamation of March 1815. Population in 1872, 5300 in the town and 6877 in the commune.  DIJON (Divio, Dibio, or Divionense Castruni), the chief town of the department of Cote-d Or in France, and formerly capital of the province of Burgundy, is situated at the foot of Mount Affrique, in a fertile plain, on the Burgundy canal, and at the confluence of the Ouche and Suzon, in 47 19 19&quot; N. lat., and 5 2- 5&quot; E. long. The streets are broad and well built of freestone, and there are fifteen squares ; an abundant supply of water is obtained from the vale of Suzon by means of a subterranean aque duct nearly eight miles in length. Among the more note worthy of the public edifices are the cathedral of St Be&quot;nigne, in the Gothic style of the 13th century, with a spire erected in 1742; the church of Notre Dame built in 1331-1445, containing a group in stone, the Assumption of the Virgin, by Dubois, and a statue of the Black Virgin, celebrated in the Middle Ages ; the church of St Michel, of the 16th century ; the general hospital, founded by Otho III. in 1 206 ; the castle, com menced in 1478 by Louis XL, and finished in 1512 by Louis XII., once a state prison, in which the duchess of Maine, Mirabeau, the Chevalier d Eon, and Toussaint Louverture were confined, and since then a barrack for gendarmes ; and the old palace of the dukes of Burgundy, or hotel de ville, rebuilt between the end of the 17th and the end of the 18th century, in which are an art collection, the archives, a museum of natural history, a school of arts, and the sa lle des gardes, containing the 