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the memorable expedition of Lewis and Clark, none was found adventurous enough to penetrate that extensive portion of our continent, more than a few hundred miles. It was almost as little known to us, as the interior of New Holland, or the deserts of Africa. After the return of those celebrated travellers, several Indian traders were induced to extend the sphere of their enterprise, and one of them, Manuel Lisa, ascended the Missouri almost to its source. These enterprising individuals meeting with considerable success, a trading company [2] or association followed, under the name of, formed in the hope of carrying on this business more extensively than it had hitherto been practised, and, in time, of rivalling even the British associations in Canada. The company was composed of twelve persons, with a capital of about forty thousand dollars. A small sum it is true, but as much as was necessary for a beginning. The company engaged about two hundred and fifty men, Canadians and Americans;