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The Arabs, who inherited the medical lore of the Greeks, and probably added to this in the case of mercury knowledge acquired from India, were much interested in mercury. In the chemical works attributed to Geber not only the metal itself, but its compounds, red precipitate and corrosive sublimate, are described. Much use of mercury was made by the Arabs in the form of ointments for skin diseases, for which Mesué recommended it, and Avicenna was probably the first physician to express doubt in regard to the poisonous nature of the metal. He observed that many persons had swallowed it without any bad effect, and he noted that it passed through the body unchanged.

Fallopius (1523-1562) remarks that in his time shepherds gave quicksilver to sheep and cattle to kill worms, and Brassavolus (1500-1554) states that he had given it to children in doses of from 2 to 20 grains, and had expelled worms by that means. Matthiolus (died 1577) relates that he had known women take a pound of it at a dose with the object of procuring abortion, and says it had not produced any bad result.

Sprengel fixes the year 1497 as that in which mercury was first employed externally for the cure of syphilis. Frictions, fumigations, and plasters were the earliest forms in which it was employed. Berenger de Carpi, a famous surgeon and anatomist of Bologna, who practised in the early part of the sixteenth century, is said