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 preparation, invented by Sylvius, was called the Carminative Spirit of Sylvius.

Mindererus's Spirit, made from distilled vinegar and the volatile spirit of hartshorn, is believed by many competent authorities to have possessed virtues which are not contained in the modern liquor ammonii acetati. The late Professor Redwood was one of these. He believed that the old preparation contained a trace of cyanic ether. The new liquor, he said, made from strong caustic solution of ammonia and strong acetic acid, "is but the ghost of the old preparation. It is as unlike the true Mindererus's Spirit as a glass of vapid distilled water is unlike the sparkling crystal water as it springs from a gushing fountain" (Pharm. Jnl., Vol. V., N.S. p. 408). Mindererus was a physician of Augsburg who died in 1621. It was Boerhaave in 1732 who advocated the use of Mindererus's Spirit and made it popular.

Eau de Luce, which was official in the P.L. 1824, under the title of Spiritus Ammoniæ Succinatus, was an ammonia compound which became popular in France, and, in some degree all over Europe, about the middle of the eighteenth century, and was apparently first sold for removing grease from cloth and other fabrics. It is said that one of the pupils of Bernard Jussieu, having been bitten by a viper, applied some of the preparation, and was cured by it. It thence acquired a medical fame, which it still retains. The P.L. formula ordered 3 drachms of mastic, 4 minims of oil of amber, and 14 minims of oil of lavender to be dissolved in 9 fluid drachms of rectified spirit, and mixed with 10 fluid ounces of solution of ammonia. In some of the Continental pharmacopœias a much larger proportion of oil of amber is prescribed, and sometimes only that and spirit of ammonia. In some