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 Little by little the Inquisition got through its work, drawing its net closer and closer about the chief offenders and allowing lesser persons to go free on doing penance. At an auto-de-fe celebrated in the Plaza de San Francisco on September 24, 1559, fourteen persons were burnt to death for heresy, including four friars and three women. A large number were sentenced to lesser penalties; and the house of Isabel de Baena, in which they met, was razed to the ground, a " pillar of infamy " being erected on the site. On December 22, 1560, a second auto was celebrated at the same place, when eight women, one being a nun, and two men, one of whom was Julianillo, were burnt. Gil, Constantino, and Ferez were burnt in effigy, and a number of friars and others were visited with lesser penalties. Some contrived to escape and fled from Spain; and a few single cases of heresy were dealt with in later years. Thus ended the history of the Reform in Seville.

At VALLADOLID the movement had already come to an end, for although it began later than at Seville, it was discovered somewhat earlier. Its founder was Agustin Cazalla, born of rich parents who had lost rank for Judaising. He had studied under Carranza at Valladolid, and afterwards at Alcalâ. In 1542 he was made chaplain and preacher to the Emperor, and till 1551 followed the Court. On his return to Spain he was made canon of Salamanca and from that time forward dwelt there or at Valladolid. He became addicted to the Reform either under Carranza's instructions or in Germany, and was confirmed in his views by Carlos de Seso, a nobleman from Italy who had married a Spanish wife and had been made corregidor of Toro. Seso had heard of justification in Italy, and became an ardent propagandist; in fact it is clear that Toro, not Valladolid, was the real birthplace of the movement in New Castile. A large number of well-born persons accepted Seso's teaching, including the licentiate Herrezuelo, Fray Domingo de Rojas, many members of the Cazalla family, and many devout ladies; and all who accepted it became teachers themselves. Zamora and Logrono, near which town Seso had a house, were affected by the movement; above all, it found its headquarters in Valladolid, where it soon had a very large following, both of rich and poor. The nuns of the rich House of Belén, outside the city, were largely involved; so were many of the clergy. Meetings and services were held frequently, and the communion administered in the house of Leonor de Vibera, Cazalla's mother.

It is not known how they were discovered, but the arrests were precipitated by the action taken at Zamora, by the Bishop, against Cristobal de Padilla, steward to the Marquesa de Alcanices, who was preaching the new doctrines there. He was able to warn his friends in the capital, some of whom fled to Navarre, and thence into France. But the greater number were already taken early in June, 1558; the